Treatment of chronic constipation: current pharmacologic approaches and future directions
J Tack, S Müller–Lissner - Clinical gastroenterology and hepatology, 2009 - Elsevier
Chronic constipation is a common condition that affects up to 27% of the population. Dietary
and lifestyle measures are usually the first-line therapy, but if these fail to have an effect then …
and lifestyle measures are usually the first-line therapy, but if these fail to have an effect then …
Constipation in long-term care
SH Tariq - Journal of the American Medical Directors Association, 2007 - Elsevier
Constipation is more common in older adults and accounts for increased physician office
visits and hospital admissions. There is lack of agreement on the definition of constipation …
visits and hospital admissions. There is lack of agreement on the definition of constipation …
Chronic constipation: current treatment options
LWC Liu - Canadian Journal of Gastroenterology and …, 2011 - Wiley Online Library
Chronic constipation is a common functional gastrointestinal disorder that affects patients of
all ages. In 2007, a consensus group of 10 Canadian gastroenterologists developed a set of …
all ages. In 2007, a consensus group of 10 Canadian gastroenterologists developed a set of …
Constipation: advances in diagnosis and treatment
A Wald - Jama, 2016 - jamanetwork.com
Importance Chronic constipation accounts for at least 8 million annual visits to health care
providers in the United States and is associated with large expenditures for diagnostic …
providers in the United States and is associated with large expenditures for diagnostic …
An open, randomised, parallel group study of lactulose versus ispaghula in the treatment of chronic constipation in adults
M Rouse, N Chapman, M Mahapatra… - … Journal of Clinical …, 1991 - Wiley Online Library
The efficacy, tolerance and acceptability of lactulose (Duphalac) and ispaghula (Fybogel
Orange) were assessed in the treatment of chronic constipation in adults. In an open …
Orange) were assessed in the treatment of chronic constipation in adults. In an open …
PEG3350 in the treatment of childhood constipation: a multicenter, double-blinded, placebo-controlled trial
S Nurko, NN Youssef, M Sabri, A Langseder… - The Journal of …, 2008 - Elsevier
OBJECTIVE: To establish the efficacy and best starting dose of polyethylene glycol (PEG)
3350 in the short-term treatment of children with functional constipation. STUDY DESIGN …
3350 in the short-term treatment of children with functional constipation. STUDY DESIGN …
Chronic constipation
AE Bharucha, A Wald - Mayo Clinic Proceedings, 2019 - Elsevier
Constipation is a common symptom that may be primary (idiopathic or functional) or
associated with a number of disorders or medications. Although most constipation is self …
associated with a number of disorders or medications. Although most constipation is self …
PEG 3350 (Transipeg) versus lactulose in the treatment of childhood functional constipation: a double blind, randomised, controlled, multicentre trial
W Voskuijl, F De Lorijn, W Verwijs, P Hogeman… - Gut, 2004 - gut.bmj.com
Background: Recently, polyethylene glycol (PEG 3350) has been suggested as a good
alternative laxative to lactulose as a treatment option in paediatric constipation. However, no …
alternative laxative to lactulose as a treatment option in paediatric constipation. However, no …
[HTML][HTML] Long-term safety and effectiveness of lubiprostone, a chloride channel (ClC-2) activator, in patients with chronic idiopathic constipation
AJ Lembo, JF Johanson, HP Parkman, SS Rao… - Digestive diseases and …, 2011 - Springer
Background Lubiprostone helps relieve constipation in short-term 4-week studies. There are
limited data on long-term pharmacological treatment with lubiprostone for chronic idiopathic …
limited data on long-term pharmacological treatment with lubiprostone for chronic idiopathic …
Efficacy of drugs in chronic idiopathic constipation: a systematic review and network meta-analysis
P Luthra, M Camilleri, NE Burr… - The Lancet …, 2019 - thelancet.com
Background There are several drugs available for the treatment of chronic idiopathic
constipation, but their relative efficacy is unclear because there have been no head-to-head …
constipation, but their relative efficacy is unclear because there have been no head-to-head …