Expression and regulation of prostaglandin receptors in the human placenta and fetal membranes at term and preterm

E Unlugedik, N Alfaidy, A Holloway, S Lye… - Reproduction …, 2010 - CSIRO Publishing
Prostaglandins (PGs) play an important role in parturition in many species, including
humans. The present study examined the distribution of PG receptor subtypes (EP1–4 and …

Localization and expression of prostaglandin E2 receptors in human placenta and corresponding fetal membranes with labor

PL Grigsby, SR Sooranna, DE Brockman… - American journal of …, 2006 - Elsevier
OBJECTIVE: The effects of prostaglandin E2 (PGE2) are mediated through G-protein
coupled receptors, acting via different second messengers. The aim of this study was to …

Expression of prostanoid receptors in human lower segment pregnant myometrium

A Leonhardt, A Glaser, M Wegmann… - … and essential fatty acids, 2003 - Elsevier
Prostanoids, especially prostaglandin (PG) E2, are important mediators of uterine relaxation
and contractions during gestation and parturition. Inhibitors of PG formation as well as PG …

Temporal and tissue-specific expression of prostaglandin receptors EP2, EP3, EP4, FP, and cyclooxygenases 1 and 2 in uterus and fetal membranes during bovine …

JA Arosh, SK Banu, P Chapdelaine, MA Fortier - Endocrinology, 2004 - academic.oup.com
Uteroplacental prostaglandins (PGs) play pivotal roles in maintenance and/or termination of
pregnancy in mammals. Regulation of PG biosynthetic and signaling mechanisms in …

Prostaglandins and prostanoid receptors in human pregnancy and parturition

DM Slater, S Zervou, S Thornton - The Journal of the Society for …, 2002 - Springer
Preterm labor occurs in up to 10% of all births but is associated with 85% of perinatal deaths
in otherwise normal babies. Elucidation of the mechanisms involved in normal labor is an …

Hormonal regulation of prostaglandin E2 receptors: localization and expression in rat cervical tissue

AC Hinton, PL Grigsby, BA Pitzer… - Reproductive …, 2010 - journals.sagepub.com
Prostaglandin E2 (PGE2) may regulate uterine activation and cervical ripening for labor
through specific contractile and relaxatory receptors (EP1-4). The aim of this study was to …

[PDF][PDF] Expression of prostanoid receptor genes in baboon chorion and decidua during pregnancy and parturition

GCS Smith, WX Wu, PW Nathanielsz - Journal of endocrinology, 2001 - Citeseer
The aim of this study was to determine whether expression of prostanoid receptor genes
varied with gestational age or labour in the decidua and chorion of baboons. Tissues were …

Decidual activation: abundance and localization of prostaglandin F2α receptor (FP) mRNA and protein and uterine activation proteins in human decidua at preterm …

S Makino, DB Zaragoza, BF Mitchell, H Yonemoto… - Placenta, 2007 - Elsevier
OBJECTIVE: To study how the decidua contributes to parturition, we examined
prostaglandin F2α concentrations as well as prostaglandin 15-hydroxy dehydrogenase …

Expression, localization and function of prostaglandin receptors in myometrium

L Myatt, SJ Lye - Prostaglandins, leukotrienes and essential fatty acids, 2004 - Elsevier
Prostaglandins (PGs) play a role in the initiation and maintenance of labor, acting via
specific relaxatory or contractile receptors on myometrium. Myometrial response to addition …

Regional expression of prostaglandin E2 and F2alpha receptors in human myometrium, amnion, and choriodecidua with advancing gestation and labor

PL Grigsby, SR Sooranna, B Adu-Amankwa… - Biology of …, 2006 - academic.oup.com
The change from uterine quiescence to enhanced contractile activity may be due to the
differential expression of prostaglandin receptors within the myometrium and fetal …