Lipolysis in skeletal muscle is rapidly regulated by low physiological doses of insulin

S Jacob, B Hauer, R Becker, S Artzner, P Grauer… - Diabetologia, 1999 - Springer
Aims/hypothesis. Both patients with Type II (non-insulin-dependent) diabetes mellitus and
normoglycaemic, insulin resistant subjects were shown to have an increased lipid content in …

Suppression of systemic, intramuscular, and subcutaneous adipose tissue lipolysis by insulin in humans

M Stumvoll, S Jacob, HG Wahl, B Hauer… - The Journal of …, 2000 - academic.oup.com
In addition to sc and visceral fat deposits, muscle has been shown to contain relevant
amounts of lipids whose breakdown is subject to hormonal regulation. The aim of the …

Evidence for a major role of skeletal muscle lipolysis in the regulation of lipid oxidation during caloric restriction in vivo

E Hagstrom-Toft, A Thorne, S Reynisdottir, E Moberg… - Diabetes, 2001 - Am Diabetes Assoc
A lipolytic process in skeletal muscle has recently been demonstrated. However, the
physiological importance of this process is unknown. We investigated the role of skeletal …

Combined Hyperinsulinemia and Hyperglycemia, But Not Hyperinsulinemia Alone, Suppress Human Skeletal Muscle Lipolytic Activity in Vivo

V Qvisth, E Hagström-Toft, S Enoksson… - The Journal of …, 2004 - academic.oup.com
Effects of circulating insulin and glucose concentrations on skeletal muscle and adipose
tissue lipolytic activity were investigated in 10 type 1 diabetes patients with no endogenous …

No apparent suppression by insulin of in vivo skeletal muscle lipolysis in nonobese women

E Moberg, S Sjöberg… - American Journal of …, 2002 - journals.physiology.org
To investigate the antilipolytic effect of insulin in skeletal muscle and adipose tissue in vivo,
the rates of glycerol release from the two tissues were compared in 10 nonobese women …

Marked heterogeneity of human skeletal muscle lipolysis at rest

E Hagstrom-Toft, V Qvisth, I Nennesmo, M Rydén… - Diabetes, 2002 - Am Diabetes Assoc
In this study, variations in lipolysis among different muscle groups were examined by
measuring local net glycerol release in vivo in healthy, normal-weight subjects (n= 11) …

Inhibition of adipose tissue lipolysis increases intramuscular lipid use in type 2 diabetic patients

LJC Van Loon, RJF Manders, R Koopman, B Kaastra… - Diabetologia, 2005 - Springer
Aims/hypothesis In the present study, we investigated the consequences of adipose tissue
lipolytic inhibition on skeletal muscle substrate use in type 2 diabetic patients. Materials and …

Human Skeletal Muscle Lipolysis Is More Responsive to Epinephrine Than to Norepinephrine Stimulation in Vivo

V Qvisth, E Hagström-Toft, S Enoksson… - The Journal of …, 2006 - academic.oup.com
Context: Triglyceride (TG) deposits in skeletal muscle (SM) are an important energy
reservoir, and increased im TG content is associated with muscle insulin resistance …

Measurements of interstitial muscle glycerol in normal and insulin-resistant subjects

M Sjöstrand, S Gudbjörnsdottir… - The Journal of …, 2002 - academic.oup.com
The aim of this project was to study the regulation of interstitial glycerol levels in muscle in
normal subjects, and to estimate interstitial muscle glycerol in obese subjects and patients …

Effects of insulin treatment in type 2 diabetic patients on intracellular lipid content in liver and skeletal muscle

C Anderwald, E Bernroider, M Krssák, H Stingl… - Diabetes, 2002 - Am Diabetes Assoc
Insulin resistance is frequently associated with increased lipid content in muscle and liver.
Insulin excess stimulates tissue lipid accumulation. To examine the effects of insulin and …