Activation of site‐specific DNA integration in human cells by a single chain integration host factor
T Corona, Q Bao, N Christ, T Schwartz, J Li… - Nucleic acids …, 2003 - academic.oup.com
The heterodimeric integration host factor (IHF) is a site‐specific DNA‐binding and DNA‐
bending protein from Escherichia coli. It plays essential roles in a variety of DNA …
bending protein from Escherichia coli. It plays essential roles in a variety of DNA …
Nucleoprotein architectures regulating the directionality of viral integration and excision
NE Seah, D Warren, W Tong… - Proceedings of the …, 2014 - National Acad Sciences
The virally encoded site-specific recombinase Int collaborates with its accessory DNA
bending proteins IHF, Xis, and Fis to assemble two distinct, very large, nucleoprotein …
bending proteins IHF, Xis, and Fis to assemble two distinct, very large, nucleoprotein …
Physical organization of DNA by multiple non-specific DNA-binding modes of integration host factor (IHF)
The integration host factor (IHF) is an abundant nucleoid-associated protein and an
essential co-factor for phage λ site-specific recombination and gene regulation in E. coli …
essential co-factor for phage λ site-specific recombination and gene regulation in E. coli …
Static kinks or flexible hinges: multiple conformations of bent DNA bound to integration host factor revealed by fluorescence lifetime measurements
M Connolly, A Arra, V Zvoda, PJ Steinbach… - The Journal of …, 2018 - ACS Publications
Gene regulation depends on proteins that bind to specific DNA sites. Such specific
recognition often involves severe DNA deformations, including sharp kinks. It has been …
recognition often involves severe DNA deformations, including sharp kinks. It has been …
Pressure dissociation of integration host factor–DNA complexes reveals flexibility-dependent structural variation at the protein–DNA interface
DF Senear, V Tretyachenko-Ladokhina… - Nucleic acids …, 2007 - academic.oup.com
E. coli Integration host factor (IHF) condenses the bacterial nucleoid by wrapping DNA.
Previously, we showed that DNA flexibility compensates for structural characteristics of the …
Previously, we showed that DNA flexibility compensates for structural characteristics of the …
Structure, dynamics, and branch migration of a DNA Holliday junction: a single-molecule fluorescence and modeling study
MA Karymov, M Chinnaraj, A Bogdanov… - Biophysical journal, 2008 - cell.com
The Holliday junction (HJ) is a central intermediate of various genetic processes, including
homologous and site-specific DNA recombination and DNA replication. Elucidating the …
homologous and site-specific DNA recombination and DNA replication. Elucidating the …
Specific and non-specific interactions of integration host factor with DNA: thermodynamic evidence for disruption of multiple IHF surface salt-bridges coupled to DNA …
JA Holbrook, OV Tsodikov, RM Saecker… - Journal of molecular …, 2001 - Elsevier
Site-specific DNA binding of architectural protein integration host factor (IHF) is involved in
formation of functional multiprotein-DNA assemblies in Escherichia coli, while non-specific …
formation of functional multiprotein-DNA assemblies in Escherichia coli, while non-specific …
Hexapeptides that inhibit processing of branched DNA structures induce a dynamic ensemble of Holliday junction conformations
Holliday junctions are critical intermediates in DNA recombination, repair, and restart of
blocked replication. Hexapeptides have been identified that bind to junctions and inhibit …
blocked replication. Hexapeptides have been identified that bind to junctions and inhibit …
[图书][B] Kinetic and steady-state studies of binding and bending of lambda phage DNA by Integration Host Factor
S Sugimura - 2005 - search.proquest.com
Abstract Integration Host Factor (IHF) is a prokaryotic protein required for the integration of λ
phage DNA into its host genome. IHF can undergo both, specific and non-specific binding to …
phage DNA into its host genome. IHF can undergo both, specific and non-specific binding to …