Site-specific DNA binding of architectural protein integration host factor (IHF) is involved in
formation of functional multiprotein-DNA assemblies in Escherichia coli, while non-specific …

Abstract Integration Host Factor (IHF) is a prokaryotic protein required for the integration of λ
phage DNA into its host genome. IHF can undergo both, specific and non-specific binding to …

Holliday junctions are critical intermediates in DNA recombination, repair, and restart of
blocked replication. Hexapeptides have been identified that bind to junctions and inhibit …

Integration host factor, IHF, is a sequence-specific DNA-binding and DNA-bending protein
composed of two related but non-identical subunits. We report the isolation and …

λ Integrase (Int) mediates recombination between attachment sites on phage and
Escherichia coli DNA. Int is assisted by accessory protein-induced DNA loops in bridging …

Azide moieties have been specifically placed in the backbone of DNA by chemical coupling
between azidophenacyl bromide and uniquely positioned phosphorothioate residues. The …

Background: Escherichia coli integration host factor (IHF) is a DNA-binding protein that
participates in a wide variety of biochemical functions. In many of its activities, IHF appears …

Holliday Junctions are critical DNA intermediates central to double strand break repair and
homologous recombination. The junctions can adopt two general forms: open and stacked …

We have investigated the isomerization dynamics and plausible energy landscape of 4-way
Holliday junctions (4WHJs) bound to integration host factor (IHF, a DNA binding protein) …

A four-stranded DNA junction (Fig. 1a) was first proposed by Robin Holliday in 1964 as a
structural intermediate in a mechanistic model to account for the means by which genetic …