Outcome of lower L-thyroxine dose for treatment of congenital hypothyroidism
SP Campos, DE Sandberg, C Barrick… - Clinical …, 1995 - journals.sagepub.com
The appropriateness of the recommended L-thyroxine dose (10-15 μg/kg/day) for the
treatment of congenital hypothyroidism has been questioned because of the risk of …
treatment of congenital hypothyroidism has been questioned because of the risk of …
Initial treatment dose of L-thyroxine in congenital hypothyroidism
KA Selva, SH Mandel, L Rien, D Sesser… - The Journal of …, 2002 - Elsevier
Objectives: To determine the optimal initial treatment dose of L-thyroxine in congenital
hypothyroidism (CH) by evaluating the time course of rise of thyroxine (T4) and free T4 …
hypothyroidism (CH) by evaluating the time course of rise of thyroxine (T4) and free T4 …
In congenital hypothyroidism, an initial l-thyroxine dose of 10–12 μg/kg/day is sufficient and sometimes excessive based on thyroid tests 1 month later
P Vaidyanathan, M Pathak… - Journal of Pediatric …, 2012 - degruyter.com
Background: Current guidelines recommend an initial L-thyroxine (L-T4) dose of 10–15
μg/kg/day for the treatment of congenital hypothyroidism (CH). We analyzed our data for the …
μg/kg/day for the treatment of congenital hypothyroidism (CH). We analyzed our data for the …
Longitudinal assessment of L-thyroxine therapy for congenital hypothyroidism
JA Germak, TP Foley Jr - The Journal of pediatrics, 1990 - Elsevier
We evaluated the longitudinal response in 43 infants with congenital primary hypothyroidism
during the first year of l-thyroxine therapy. Diagnosis was confirmed by serum thyroid …
during the first year of l-thyroxine therapy. Diagnosis was confirmed by serum thyroid …
A thyroxine dosage of 8 μg/kg per day is appropriate for the initial treatment of the majority of infants with congenital hypothyroidism
G Touati, J Leger, JE Toublanc, JP Farriaux… - European journal of …, 1997 - Springer
The adequate l-thyroxine dosage for the initial treatment of infants with congenital
hypothyroidism is a subject of controversy. Some recommend higher dosages (> 10 …
hypothyroidism is a subject of controversy. Some recommend higher dosages (> 10 …
High and low dose initial thyroxine therapy for congenital hypothyroidism
Objective: To assess factors influencing thyroxine (T4 levels 1 month after initiating
replacement therapy for congenital primary hypothyroidism. Methodology: A retrospective …
replacement therapy for congenital primary hypothyroidism. Methodology: A retrospective …
Long-term effects of L-thyroxine therapy for congenital hypothyroidism
JF Rovet, RM Ehrlich - The Journal of pediatrics, 1995 - Elsevier
Objective: To study the effects of initial and concurrent dose levels of L-thyroxine on ability
and behavior in children with congenital hypothyroidism. Methods: An existing database …
and behavior in children with congenital hypothyroidism. Methods: An existing database …
In search of the optimal therapy for congenital hypothyroidism
JF Rovet - The Journal of pediatrics, 2004 - jpeds.com
Neonatal thyroid screening programs were first im-plemented in the mid-to late 1970s to
detect congenital hypothyroidism (CH) as soon after birth as possible and begin therapy …
detect congenital hypothyroidism (CH) as soon after birth as possible and begin therapy …
Thyroxine dose for congenital hypothyroidism
RM Ehrlich - Clinical Pediatrics, 1995 - journals.sagepub.com
The symptoms and signs develop over the ensuing weeks of extra-uterine life. Only in the
severest cases are subtle signs of hypothy-roidism present at birth, such as prolonged …
severest cases are subtle signs of hypothy-roidism present at birth, such as prolonged …
How should we be treating children with congenital hypothyroidism?
SH LaFranchi, J Austin - Journal of Pediatric Endocrinology and …, 2007 - degruyter.com
Early detection by newborn screening and appropriate L-thyroxine treatment leads to normal
or near-normal neurocognitive outcome in infants with congenital hypothyroidism. Many …
or near-normal neurocognitive outcome in infants with congenital hypothyroidism. Many …
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