Osteoarthritis (OA) is a multifactorial disease. Different risk factors have been identified such
as aging and obesity and different models have been used to study the impact of obesity …

Adipokines are proteins produced by white adipose tissue, which is an active secretory
organ. Regulation of immune and inflammatory responses is among the multiple …

Purpose Our aim was to investigate whether serum and synovial-fluid (SF) concentrations of
interleukin-6 (IL-6), leptin, adiponectin, resistin or visfatin are associated with joint pain in hip …

We performed a systematic literature review to summarize the underlying pathogenic
mechanisms by which adipokines influence rheumatological diseases and the resulting …

In the last two decades we have witnessed a boost in scientific interest and knowledge of
adipose tissue biology to such an extent that it was promoted to an active endocrine organ …

Background Associations between adipokines and bone mineral density (BMD) in knee
osteoarthritis (OA) remain indistinct. The aim of this study was to investigate the cross …

The discovery of leptin in 1994 marked the beginning of a new understanding about white
adipose tissue (WAT) and modified a static vision of this tissue which was viewed up to the …

Inflammation is a complex mechanism of cell/tissue responses to injuries triggered by
multiple causes, including trauma, pathogens or autoimmune abnormal responses. In the …

Osteoarthritis (OA) is a debilitating condition characterized by inflammation, breakdown, and
consequent loss of cartilage of the joints. Epidemiological studies indicate obesity is an …

Objective. Limited studies have explored the association between adipokines and knee OA
structural progression using quantitative MRI (qMRI), and very few have included total knee …