[HTML][HTML] PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system

PM Castillo, M de la Mata, MF Casula… - Beilstein Journal of …, 2014 - beilstein-journals.org
Abstract Camptothecin (CPT;(S)-(+)-4-ethyl-4-hydroxy-1H-pyrano [3', 4': 6, 7] indolizino [1, 2-
b] quinoline-3, 14-(4H, 12H)-dione) is a highly cytotoxic natural alkaloid that has not yet …

Cyclodextrin–PEG conjugate-wrapped magnetic ferrite nanoparticles for enhanced drug loading and release

IVMV Enoch, S Ramasamy, S Mohiyuddin… - Applied …, 2018 - Springer
Magnetic nanoparticles are envisaged to overcome the impediments in the methods of
targeted drug delivery and hence cure cancer effectively. We report herein, manganese …

Biodegradable magnetic microspheres for drug targeting, temperature controlled drug release, and hyperthermia

D Zahn, A Weidner, K Saatchi, UO Häfeli… - Current Directions in …, 2019 - degruyter.com
Magnetic microspheres (MMS) used for magnetic drug targeting consist of magnetic
nanoparticles (MNP) and a pharmaceutical agent embedded in a polymeric matrix material …

Chitosan-poly(acrylic acid) complex modified paramagnetic Fe3O4 nanoparticles for camptothecin loading and release

A Zhu, X Luo, S Dai - Journal of Materials Research, 2009 - Springer
The stable superparamagnetic colloidal suspension of chitosan-poly (acrylic acid)(CS-
PAA)/Fe 3 O 4 nanoparticles was synthesized by graft copolymerization AA on the surface of …

Surface‐Functionalized Ultrasmall Superparamagnetic Nanoparticles as Magnetic Delivery Vectors for Camptothecin

F Cengelli, JA Grzyb, A Montoro… - ChemMedChem …, 2009 - Wiley Online Library
Drug–nanoparticle conjugates: The anticancer drug camptothecin (CPT) was covalently
linked at the surface of ultrasmall superparamagnetic iron oxide nanoparticles (USPIOs) via …

Development and characterization of magnetite/poly (butylcyanoacrylate) nanoparticles for magnetic targeted delivery of cancer drugs

M López-Viota, MM El-Hammadi, L Cabeza… - AAPS …, 2017 - Springer
A great attention is presently paid to the design of drug delivery vehicles based on surface-
modified magnetic nanoparticles. They can, in principle, be directed to a desired target area …

Temperature controlled camptothecin release from biodegradable magnetic PLGA microspheres

D Zahn, A Weidner, Z Nosrati, L Wöckel, J Dellith… - Journal of Magnetism …, 2019 - Elsevier
Drug loaded magnetic microspheres (MMS) can be magnetically guided to a target area
within the body, where the pharmaceutical agent is released passively. For a faster release …

Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug

P Krishnan, M Rajan, S Kumari, S Sakinah, SP Priya… - Scientific reports, 2017 - nature.com
Camptothecin (CPT) is an anti-cancer drug that effectively treats various cancers, including
colon cancer. However, poor solubility and other drawbacks have restricted its …

PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: preparation, characterization and cytotoxicity …

JB Qu, HH Shao, GL Jing, F Huang - Colloids and surfaces B: Biointerfaces, 2013 - Elsevier
A magnetic nano-sized carrier for 10-hydroxycamptothecin (HCPT) was prepared by using
Fe3O4 nanoparticles as cores and chitosan (CS) as a polymeric shell by a novel reverse …

Functionalized magnetic nanoparticles as vehicles for the delivery of the antitumor drug gemcitabine to tumor cells. Physicochemical in vitro evaluation

JL Viota, A Carazo, JA Munoz-Gamez, K Rudzka… - Materials Science and …, 2013 - Elsevier
Gemcitabine is a chemotherapy drug used in different carcinomas, although because it
displays a short biological half-life, its plasmatic levels can quickly drop below the effective …