Neurodevelopmental toxicity of methylmercury: Laboratory animal data and their contribution to human risk assessment
AF Castoldi, N Onishchenko, C Johansson… - Regulatory Toxicology …, 2008 - Elsevier
Methylmercury (MeHg) is one of the most significant public health hazards. The clinical
findings in the victims of the Japanese and Iraqi outbreaks have disclosed the pronounced …
findings in the victims of the Japanese and Iraqi outbreaks have disclosed the pronounced …
Human developmental neurotoxicity of methylmercury: impact of variables and risk modifiers
AF Castoldi, C Johansson, N Onishchenko… - Regulatory Toxicology …, 2008 - Elsevier
Methylmercury (MeHg) is a widespread environmental and food toxicant which has long
been known to affect neurodevelopment in both humans and experimental animals. Risk …
been known to affect neurodevelopment in both humans and experimental animals. Risk …
Methylmercury developmental neurotoxicity: a comparison of effects in humans and animals
TM Burbacher, PM Rodier, B Weiss - Neurotoxicology and teratology, 1990 - Elsevier
A qualitative and quantitative comparison of the neuropathological and neurobehavioral
effects of early methylmercury (MeHg) exposure is presented. The focus of the qualitative …
effects of early methylmercury (MeHg) exposure is presented. The focus of the qualitative …
Effect of methylmercury on midbrain cell proliferation during organogenesis: potential cross-species differences and implications for risk assessment
TA Lewandowski, RA Ponce, JS Charleston… - Toxicological …, 2003 - academic.oup.com
bromodeoxyuridine (BrdU) labeling was employed to explore the effects of methylmercury
(MeHg) on cell cycle kinetics in the developing rat midbrain during gestational days (GDs) …
(MeHg) on cell cycle kinetics in the developing rat midbrain during gestational days (GDs) …
Perinatal and lifetime exposure to methylmercury in the mouse: behavioral effects
This project was undertaken to more completely understand the consequences of lifetime
exposure to methylmercury. A series of experiments examined how perinatal or lifetime …
exposure to methylmercury. A series of experiments examined how perinatal or lifetime …
Neurobehavioural and molecular changes induced by methylmercury exposure during development
C Johansson, AF Castoldi, N Onishchenko… - Neurotoxicity …, 2007 - Springer
There is an increasing body of evidence on the possible environmental influence on
neurodevelopmental and neurodegenerative disorders. Both experimental and …
neurodevelopmental and neurodegenerative disorders. Both experimental and …
Methylmercury and brain development: imprecision and underestimation of developmental neurotoxicity in humans
P Grandjean, KT Herz - Mount Sinai Journal of Medicine: A …, 2011 - Wiley Online Library
Methylmercury is now recognized as an important developmental neurotoxicant, though this
insight developed slowly over many decades. Developmental neurotoxicity was first …
insight developed slowly over many decades. Developmental neurotoxicity was first …
Neurotoxicity and molecular effects of methylmercury
AF Castoldi, T Coccini, S Ceccatelli, L Manzo - Brain research bulletin, 2001 - Elsevier
The neurotoxicity of high levels of methylmercury (MeHg) and the high susceptibility of the
developing brain are well established both in humans and experimental animals. Prenatally …
developing brain are well established both in humans and experimental animals. Prenatally …
Neurobehavioral effects of developmental methylmercury exposure.
SG Gilbert, KS Grant-Webster - Environmental health …, 1995 - ehp.niehs.nih.gov
Methylmercury (MeHg) is a global environmental problem and is listed by the International
Program of Chemical Safety as one of the six most dangerous chemicals in the world's …
Program of Chemical Safety as one of the six most dangerous chemicals in the world's …
Neurobehavioral effect of chronic and bolus doses of methylmercury following prenatal exposure in C57BL/6 weanling mice
J Liang, M Inskip, D Newhook, C Messier - Neurotoxicology and teratology, 2009 - Elsevier
Several studies with animals have shown that even low and medium prenatal and postnatal
exposure to methylmercury (MeHg) can result in locomotor, motor coordination and learning …
exposure to methylmercury (MeHg) can result in locomotor, motor coordination and learning …