Emerging concepts in autoimmune encephalomyelitis beyond the CD4/TH1 paradigm
H Batoulis, K Addicks, S Kuerten - Annals of Anatomy-Anatomischer …, 2010 - Elsevier
Multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis
(EAE) have long been regarded as primarily T helper cell type 1-mediated diseases …
(EAE) have long been regarded as primarily T helper cell type 1-mediated diseases …
Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination
A Rostami, B Ciric - Journal of the neurological sciences, 2013 - Elsevier
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). The
etiology of MS is not well understood, but it is believed that myelin-specific CD4+ T cells play …
etiology of MS is not well understood, but it is believed that myelin-specific CD4+ T cells play …
Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …
Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis
HS Domingues, M Mues, H Lassmann, H Wekerle… - PloS one, 2010 - journals.plos.org
Background There is consensus that experimental autoimmune encephalomyelitis (EAE)
can be mediated by myelin specific T cells of Th1 as well as of Th17 phenotype, but the …
can be mediated by myelin specific T cells of Th1 as well as of Th17 phenotype, but the …
Th17 cells in central nervous system autoimmunity
C Sie, T Korn, M Mitsdoerffer - Experimental neurology, 2014 - Elsevier
Multiple sclerosis (MS) is the most important autoimmune disease of the central nervous
system (CNS). Its animal model experimental autoimmune encephalomyelitis (EAE) has …
system (CNS). Its animal model experimental autoimmune encephalomyelitis (EAE) has …
[HTML][HTML] Cytokines and effector T cell subsets causing autoimmune CNS disease
F Petermann, T Korn - FEBS letters, 2011 - Elsevier
Although experimental autoimmune encephalomyelitis (EAE) is limited in its potency to
reproduce the entirety of clinical and histopathologic features of multiple sclerosis (MS), this …
reproduce the entirety of clinical and histopathologic features of multiple sclerosis (MS), this …
Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response
Multiple sclerosis is considered a disease of complex autoimmune etiology, yet there
remains a lack of consensus as to specific immune effector mechanisms. Recent analyses of …
remains a lack of consensus as to specific immune effector mechanisms. Recent analyses of …
Experimental autoimmune encephalomyelitis–achievements and prospective advances
H Batoulis, MS Recks, K Addicks, S Kuerten - Apmis, 2011 - Wiley Online Library
Batoulis H, Recks MS, Addicks K, Kuerten S. Experimental autoimmune encephalomyelitis–
achievements and prospective advances. APMIS 2011; 119: 819–30. Multiple sclerosis (MS) …
achievements and prospective advances. APMIS 2011; 119: 819–30. Multiple sclerosis (MS) …
Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis
RA O'Connor, CT Prendergast, CA Sabatos… - The Journal of …, 2008 - journals.aai.org
It has recently been proposed that experimental autoimmune encephalomyelitis, once
considered the classical Th1 disease, is predominantly Th17 driven. In this study we show …
considered the classical Th1 disease, is predominantly Th17 driven. In this study we show …
T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
JM Fletcher, SJ Lalor, CM Sweeney… - Clinical & …, 2010 - academic.oup.com
Multiple sclerosis (MS) is a demyelinating inflammatory disorder of the central nervous
system (CNS), which involves autoimmune responses to myelin antigens. Studies in …
system (CNS), which involves autoimmune responses to myelin antigens. Studies in …