Cancer stem cell: fundamental experimental pathological concepts and updates

F Islam, B Qiao, RA Smith, V Gopalan… - … and molecular pathology, 2015 - Elsevier
Cancer stem cells (CSCs) are a subset of cancer cells which play a key role in predicting the
biological aggressiveness of cancer due to its ability of self-renewal and multi-lineage …

Overview of cancer stem cells and stemness for community oncologists

JD Lathia, H Liu - Targeted oncology, 2017 - Springer
Advances in cancer research in the past have led to an evolving understanding of cancer
pathogenesis and the development of novel drugs that significantly improve patient …

Cancer stem cells and chemoresistance: The smartest survives the raid

J Zhao - Pharmacology & therapeutics, 2016 - Elsevier
Chemoresistant metastatic relapse of minimal residual disease plays a significant role for
poor prognosis of cancer. Growing evidence supports a critical role of cancer stem cell …

[HTML][HTML] Stem cells in cancer therapy: opportunities and challenges

CL Zhang, T Huang, BL Wu, WX He, D Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Metastatic cancer cells generally cannot be eradicated using traditional surgical or
chemoradiotherapeutic strategies, and disease recurrence is extremely common following …

Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies

L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Translational potential of cancer stem cells: A review of the detection of cancer stem cells and their roles in cancer recurrence and cancer treatment

F Islam, V Gopalan, RA Smith, AKY Lam - Experimental cell research, 2015 - Elsevier
Cancer stem cells (CSCs) are a subpopulation of cancer cells with many clinical implications
in most cancer types. One important clinical implication of CSCs is their role in cancer …

The cross talk between cancer stem cells/cancer initiating cells and tumor microenvironment: the missing piece of the puzzle for the efficient targeting of these cells …

S Ravindran, S Rasool, C Maccalli - Cancer Microenvironment, 2019 - Springer
Abstract Cancer Stem Cells/Cancer Initiating Cells (CSCs/CICs) is a rare sub-population
within a tumor that is responsible for tumor formation, progression and resistance to …

In vitro models of cancer stem cells and clinical applications

S S. Franco, K Szczesna, MS Iliou, M Al-Qahtani… - BMC cancer, 2016 - Springer
Cancer cells, stem cells and cancer stem cells have for a long time played a significant role
in the biomedical sciences. Though cancer therapy is more effective than it was a few years …

Cancer stem cells in solid tumors

LE Ailles, IL Weissman - Current opinion in biotechnology, 2007 - Elsevier
Cancer stem cells (CSCs) are cells that drive tumorigenesis, as well as giving rise to a large
population of differentiated progeny that make up the bulk of the tumor, but that lack …

Current status and issues in cancer stem cell study

YM Yang, JW Chang - Cancer investigation, 2008 - Taylor & Francis
Cancer stem cells (CSCs) have been positively identified and successfully isolated from
some but not all cancers. The studies on CSCs to date suggest that these cells are rare …