Background Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron
disease. Due to the limited knowledge about potential biomarkers that help in early …

Amyotrophic lateral sclerosis (ALS) is described as a fatal and rapidly progressive
neurodegenerative disorder caused by the degeneration of upper motor neurons in the …

Neuroinflammation plays an important role in amyotrophic lateral sclerosis (ALS)
pathogenesis. However, it is difficult to evaluate inflammation of the central nervous system …

Background Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative
disorder (NDS) with unclear pathophysiology and few therapeutic options. Mutations in …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Given its prevalence, reliable biomarkers for early diagnosis are required …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized
by the deposition of misfolded proteins leading to the death of motor neurons. Several ALS …

Background Amyotrophic lateral sclerosis (ALS) is a multifactorial, multisystem motor neuron
disease for which currently there is no effective treatment. There is an urgent need to identify …

Amyotrophic lateral sclerosis (ALS) is a progressive adult-onset neurodegenerative disease,
that affects cortical, bulbar and spinal motor neurons, and it is considered a proteinopathy, in …

Recently, there has been growing interest in exosomal biomarkers for their active targeting
and specificity for delivering their cargos (proteins, lipids, nucleic acids) from the parent cell …

Exosomes contain many proteins associated with neurodegenerative diseases. To identify
new candidate biomarkers and proteins associated with amyotrophic lateral sclerosis (ALS) …