Nanoparticles: characteristics, mechanisms of action, and toxicity in pulmonary drug delivery—a review

S Gill, R Löbenberg, T Ku, S Azarmi… - Journal of …, 2007 - ingentaconnect.com
The pulmonary route has recently gained momentum as a suitable avenue for drug delivery.
The large alveolar surface area of approximately 75 m2 coupled with the thin epithelial …

Therapeutic nanostructures for pulmonary drug delivery

Y Javadzadeh, S Yaqoubi - Nanostructures for drug delivery, 2017 - Elsevier
Pulmonary drug delivery has attracted tremendous interest in the past two decades. In order
to get both local and systemic effects, lungs as the main part of the respiratory system offer …

Inhaled nanoparticles—a current review

W Yang, JI Peters, RO Williams III - International journal of pharmaceutics, 2008 - Elsevier
The field of nanotechnology may hold the promise of significant improvements in the health
and well being of patients, as well as in manufacturing technologies. The knowledge of this …

Inhaled nanoparticles–An updated review

T Praphawatvet, JI Peters, RO Williams III - International journal of …, 2020 - Elsevier
We are providing an update to our previously published review paper on inhaled
nanoparticles, thus updating with the most recent reports in the literature. The field of …

Medical nanoparticles for next generation drug delivery to the lungs

SH van Rijt, T Bein, S Meiners - 2014 - Eur Respiratory Soc
Respiratory diseases are an increasing burden for the ageing population. Although our
understanding of these diseases has improved significantly over the past decades …

Inhalative nanomedicine—opportunities and challenges

M Bur, A Henning, S Hein, M Schneider… - Inhalation …, 2009 - Taylor & Francis
Inhalation therapy is still limited by the low bioavailability of the administered drugs.
Advantages of the pulmonary administration site like large resorption area, low enzymatic …

Targeted delivery of nanoparticles for the treatment of lung diseases

S Azarmi, WH Roa, R Löbenberg - Advanced drug delivery reviews, 2008 - Elsevier
Targeted delivery of drug molecules to organs or special sites is one of the most challenging
research areas in pharmaceutical sciences. By developing colloidal delivery systems such …

Nanoparticle formulations in pulmonary drug delivery

MM Bailey, CJ Berkland - Medicinal research reviews, 2009 - Wiley Online Library
The advent of nanotechnology has reignited interest in the lungs as a major route of drug
delivery for both systemic and local treatments. The large surface area of the lungs and the …

The nanoscale in pulmonary delivery. Part 1: deposition, fate, toxicology and effects

PGA Rogueda, D Traini - Expert opinion on drug delivery, 2007 - Taylor & Francis
This two-part review explores the nanoscale in inhalation delivery. The first part covers the
deposition, fate, toxicity and effects of nanoparticles delivered via inhalation. The second …

Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …