Health impact and toxicological effects of nanomaterials in the lung
The manufacture, use and disposal of nanomaterials will result in increased human
exposures to engineered nanoparticles (ENPs), potentially via the lung. ENPs differ …
exposures to engineered nanoparticles (ENPs), potentially via the lung. ENPs differ …
[HTML][HTML] The use of nanoparticles for targeted drug delivery in non-small cell lung cancer
JE Holder, C Ferguson, E Oliveira, C Lodeiro… - Frontiers in …, 2023 - frontiersin.org
Lung cancer is a global health problem affecting millions of people each year. Non-small
cell lung cancer (NSCLC) is the most common form of lung cancer with various conventional …
cell lung cancer (NSCLC) is the most common form of lung cancer with various conventional …
Delivery strategies for sustained drug release in the lungs
C Loira-Pastoriza, J Todoroff, R Vanbever - Advanced drug delivery reviews, 2014 - Elsevier
Drug delivery to the lungs by inhalation offers a targeted drug therapy for respiratory
diseases. However, the therapeutic efficacy of inhaled drugs is limited by their rapid …
diseases. However, the therapeutic efficacy of inhaled drugs is limited by their rapid …
Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model
M Beck-Broichsitter, J Gauss, CB Packhaeuser… - International journal of …, 2009 - Elsevier
The use of colloidal carrier systems for pulmonary drug delivery is an emerging field of
interest in nanomedicine. The objective of this study was to compare the pulmonary …
interest in nanomedicine. The objective of this study was to compare the pulmonary …
[HTML][HTML] Pulmonary inhalation for disease treatment: Basic research and clinical translations
B Wang, L Wang, Q Yang, Y Zhang, T Qinglai, X Yang… - Materials Today Bio, 2024 - Elsevier
Pulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with
few systemic side effects. In addition, it is non-invasive and has good patient compliance …
few systemic side effects. In addition, it is non-invasive and has good patient compliance …
Physicochemical properties of nanoparticles affecting their fate and the physiological function of pulmonary surfactants
Q Liu, J Guan, R Song, X Zhang, S Mao - Acta biomaterialia, 2022 - Elsevier
Pulmonary drug delivery has drawn great attention due to its targeted local lung action,
reduced side effects, and ease of administration. However, inhaled nanoparticles (NPs) …
reduced side effects, and ease of administration. However, inhaled nanoparticles (NPs) …
New perspectives in nanotherapeutics for chronic respiratory diseases
Abstract According to the World Health Organization (WHO), hundreds of millions of people
of all ages and in all countries suffer from chronic respiratory diseases, with particular …
of all ages and in all countries suffer from chronic respiratory diseases, with particular …
Critical determinants of uptake and translocation of nanoparticles by the human pulmonary alveolar epithelium
AJ Thorley, P Ruenraroengsak, TE Potter, TD Tetley - Acs Nano, 2014 - ACS Publications
The ability to manipulate the size and surface properties of nanomaterials makes them a
promising vector for improving drug delivery and efficacy. Inhalation is a desirable route of …
promising vector for improving drug delivery and efficacy. Inhalation is a desirable route of …
Nanocarriers as pulmonary drug delivery systems to treat and to diagnose respiratory and non respiratory diseases
M Smola, T Vandamme… - International journal of …, 2008 - Taylor & Francis
The purpose of this review is to discuss the impact of nanocarriers administered by
pulmonary route to treat and to diagnose respiratory and non respiratory diseases. Indeed …
pulmonary route to treat and to diagnose respiratory and non respiratory diseases. Indeed …
Pulmonary targeting with biodegradable salbutamol-loaded nanoparticles
M Beck-Broichsitter, J Gauss, T Gessler… - Journal of aerosol …, 2010 - liebertpub.com
Background: Aerosol therapy using particulate drug carriers has become an increasingly
attractive method to deliver therapeutic or diagnostic compounds to the lung. Polymeric …
attractive method to deliver therapeutic or diagnostic compounds to the lung. Polymeric …