Exposure to mild hypoxia elicits a characteristic cerebrovascular response in mammals,
including humans. Initially, cerebral blood flow (CBF) increases as much as twofold. The …

The purpose of this study was to determine the changes in human cerebrovascular function
associated with intermittent poikilocapnic hypoxia (IH). Healthy men (n= 8; 24±1 years) were …

The effect of moderately extended, intermittent-hypoxia (IH) on cerebral perfusion during
changes in CO2 was unknown. Thus, we assessed the changes in cerebral vascular …

Breathing 100% O2 at 1 atmosphere absolute (ATA) is known to be associated with a
decrease in cerebral blood flow (CBF). It is also accompanied by a fall in arterial Pco2 …

Effects of hypoxia on cerebral circulation are important for occupational, high-altitude, and
aviation medicine. Increased risk of fainting might be attributable to altered cerebral …

This study examined the effect of high, normal, and uncontrolled end-tidal Pco2 (PetCO2) on
the ventilatory, peak cerebral blood flow velocity (V̄ p), and mean arterial blood pressure …

In humans, cerebrovascular responses to alterations in arterial Pco2 and Po2 are well
documented. However, few studies have investigated human coronary vascular responses …

Acute mountain sickness (AMS) is a common condition occurring within hours of rapid
exposure to high altitude. Despite its frequent occurrence, the pathophysiological …

It remains unknown whether hypobaria plays a role on cerebrovascular reactivity to CO2
(CVR). The present study evaluated the putative effect of hypobaria on CVR and its …

We tested the hypothesis that intermittent hypoxia (IH) and/or continuous hypoxia (CH)
would enhance the ventilatory response to acute hypoxia (HVR), thereby altering blood …