Rats were exposed to hypobaric hypoxia (0.5 atm) for up to 3 wk. Hypoxic rats failed to gain
weight but maintained normal brain water and ion content. Blood hematocrit was increased …

The effect of hypoxic-hypocapnia (P a O 2, 35 mm Hg, P a CO 2, 22 mm Hg) on regional
cerebral O 2 consumption and supply was determined in 18 α-chloralose-anesthetized open …

Background Monitoring cerebral saturation is increasingly seen as an aid to management of
patients in the operating room and in neurocritical care. How best to manipulate cerebral …

Aim: Acute hypobaric hypoxia is well known to alter brain circulation and to cause
neuropsychological impairment. However, very few studies have examined the regional …

With exposure to acute normobaric hypoxia, global cerebral oxygen delivery is maintained
via increases in cerebral blood flow (CBF); therefore, regional and localized changes in …

The benefit of induced hyperventilation for intracranial pressure (ICP) control after severe
traumatic brain injury (TBI) is controversial. In this study, we investigated the impact of early …

We simultaneously measured respiratory, cerebrovascular and cardiovascular responses to
10-min of isoxic hypoxia at three constant CO2 tensions in 15 subjects. We observed four …

Cerebral blood flow (CBF), systemic hemodynamics, and arterial blood gases were
measured during control conditions and during and after exposure to either 300 kPa O2 …

We sought to determine the influence of sympathoexcitation on dynamic cerebral
autoregulation (CA), cerebrovascular reactivity, and ventilatory control in humans at high …

Aim: Inter‐individual variations in normal human cerebral blood flow (CBF) at rest condition
have been reported. Inter‐individual variation of cerebral vascular tone is considered to …