Current management of childhood acute myeloid leukemia

JE Rubnitz - Pediatric Drugs, 2017 - Springer
The outcome for children with acute myeloid leukemia (AML) has improved significantly over
the past 30 years, with complete remission and overall survival rates exceeding 90 and …

Childhood acute myeloid leukemia

JE Rubnitz - Current Treatment Options in Oncology, 2008 - Springer
Opinion statement Despite the use of intensive chemotherapy and hematopoietic stem cell
transplantation, approximately one-third of children with acute myeloid leukemia (AML) still …

Overview of therapy and strategies for optimizing outcomes in de novo pediatric acute myeloid leukemia

K Faulk, L Gore, T Cooper - Pediatric Drugs, 2014 - Springer
Although acute myelogenous leukemia (AML) accounts for< 20% of leukemia in children, it
is responsible for over half of all pediatric leukemia deaths. Improvement in event-free …

[HTML][HTML] Pediatric acute myeloid leukemia: towards high-quality cure of all patients

GJL Kaspers, CM Zwaan - haematologica, 2007 - haematologica.org
Prognosis of childhood acute myeloid leukemia (AML) has improved significantly over the
past decades, from nearly no child surviving to a present probability of cure of approximately …

[HTML][HTML] Treatments for children and adolescents with AML

H Kim - Blood research, 2020 - ncbi.nlm.nih.gov
In recent decades, survival rates for childhood acute myeloid leukemia have remarkably
improved, owing to chemotherapy intensification, allogeneic hematopoietic stem cell …

Pediatric acute myeloid leukemia

GJL Kaspers - Expert review of anticancer therapy, 2012 - Taylor & Francis
Pediatric acute myeloid leukemia (AML) is currently associated with survival rates as high as
70%. However, many events still occur, side effects are significant, and late effects occur and …

Pediatric AML: from biology to clinical management

JDE De Rooij, CM Zwaan… - Journal of clinical …, 2015 - mdpi.com
Pediatric acute myeloid leukemia (AML) represents 15%–20% of all pediatric acute
leukemias. Survival rates have increased over the past few decades to~ 70%, due to …

Pediatric acute myeloid leukemia: updates on biology, risk stratification, and therapy

CW Elgarten, R Aplenc - Current Opinion in Pediatrics, 2020 - journals.lww.com
Further incorporation of genomic and molecular data in pediatric AML will allow for
additional refinements in risk stratification to enable the tailoring of treatment intensity. These …

Acute myeloid leukemia in children: emerging paradigms in genetics and new approaches to therapy

SE Conneely, AM Stevens - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Acute myeloid leukemia (AML) in children remains a
challenging disease to cure with suboptimal outcomes particularly when compared to the …

Clinical challenges in de novo pediatric acute myeloid leukemia

K Klein, V de Haas, GJL Kaspers - Expert Review of Anticancer …, 2018 - Taylor & Francis
Introduction: Although the prognosis of pediatric acute myeloid leukemia (pAML) has
improved, with current survival rates up to 75%, relapse rates remain high. Areas covered …