Quantitative detection of anti-PLA2R antibodies targeting different epitopes and its clinical application in primary membranous nephropathy
Y Qin, Q Wu, H Sheng, T Li, X Liu, X Yang… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives This study aimed to establish time-resolved fluorescence immunoassays to
quantitatively detect the autoantibodies targeting different epitopes of M-type phospholipase …
quantitatively detect the autoantibodies targeting different epitopes of M-type phospholipase …
[HTML][HTML] Predictive value of the domain specific PLA2R antibodies for clinical remission in patients with primary membranous nephropathy: A retrospective study
K Zhou, J Zhou, L Zhou, J Xue, B Liu, Z Zhang… - Plos one, 2024 - journals.plos.org
Background M-type phospholipase A2 receptor (PLA2R) is a major auto-antigen of primary
membranous nephropathy (PMN). Anti-PLA2R antibody levels are closely associated with …
membranous nephropathy (PMN). Anti-PLA2R antibody levels are closely associated with …
[HTML][HTML] Quantitative detection and prognostic value of antibodies against M-type phospholipase A2 receptor and its cysteine-rich ricin domain and C-type lectin …
X Liu, J Xue, T Li, Q Wu, H Sheng, X Yang, B Lin… - Plos one, 2024 - journals.plos.org
Background M-type phospholipase A2 receptor (PLA2R) is the major autoantigen in adult
idiopathic membranous nephropathy (IMN). Although reactive epitopes in the PLA2R …
idiopathic membranous nephropathy (IMN). Although reactive epitopes in the PLA2R …
[HTML][HTML] The value of PLA2R antigen and IgG subclass staining relative to anti-PLA2R seropositivity in the differential diagnosis of membranous nephropathy
D Bajcsi, L Bitó, S Turkevi-Nagy, T Nyári, É Kemény… - BMC nephrology, 2023 - Springer
Background The diagnostic performance of PLA2R and IgG subclass staining of kidney
biopsies relative to anti-PLA2R seropositivity in the differentiation of primary and secondary …
biopsies relative to anti-PLA2R seropositivity in the differentiation of primary and secondary …
[HTML][HTML] Development of a standardized chemiluminescence immunoassay for the detection of autoantibodies against human M-type phospholipase A2 receptor in …
C Dähnrich, S Saschenbrecker, I Gunnarsson… - Kidney International …, 2020 - Elsevier
Introduction Autoantibodies against the M-type phospholipase A2 receptor (PLA2R) are
important markers in the diagnosis and monitoring of primary membranous nephropathy …
important markers in the diagnosis and monitoring of primary membranous nephropathy …
[HTML][HTML] Secretory expression and purification of recombinant PLA2R epitopes for the detection of anti-PLA2R autoantibody in serum
X Xu, T Xiang, S Song, A Wu, L Liu, L Xu, C Xu… - Analyst, 2022 - pubs.rsc.org
Most patients with idiopathic membranous nephropathy (IMN) have autoimmune antibodies
specifically against the M-type phospholipase A2 receptor (PLA2R). PLA2R acts as a …
specifically against the M-type phospholipase A2 receptor (PLA2R). PLA2R acts as a …
Cross-reactivity of anti-PLA2R1 autoantibodies to rabbit and mouse PLA2R1 antigens and development of two novel ELISAs with different diagnostic performances in …
B Seitz-Polski, G Dolla, C Payré, NM Tomas… - Biochimie, 2015 - Elsevier
About 70% of patients with idiopathic membranous nephropathy (iMN) have autoantibodies
to the phospholipase A2 receptor PLA2R1. We screened sera from iMN patients for their …
to the phospholipase A2 receptor PLA2R1. We screened sera from iMN patients for their …
[HTML][HTML] A new chemiluminescence immunoassay for phospholipase A2 receptor 1 autoantibodies allows early identification of autoantibody recurrence in patients …
E Hoxha, RAK Stahl, L Reinhard, A Kühnl… - Kidney International …, 2021 - Elsevier
Background Circulating autoantibodies against the M-type phospholipase A 2 receptor 1
(PLA 2 R1) are important biomarkers in membranous nephropathy (MN), supporting the …
(PLA 2 R1) are important biomarkers in membranous nephropathy (MN), supporting the …
Serum antibody and glomerular antigen of antiphospholipase A2 receptor in Chinese patients with idiopathic membranous nephropathy
Q Zhang, M Wu, Z Hu, X Liu, B Huang… - BioMed Research …, 2020 - Wiley Online Library
Background. M‐type phospholipase A2 receptor (PLA2R) is the first autoantigen responsible
for idiopathic membranous nephropathy (IMN). However, serum PLA2R antibody (PLA2R …
for idiopathic membranous nephropathy (IMN). However, serum PLA2R antibody (PLA2R …
[HTML][HTML] Anti-phospholipase A2 receptor (PLA2R) antibody and glomerular PLA2R expression in Japanese patients with membranous nephropathy
K Hihara, M Iyoda, S Tachibana, K Iseri, T Saito… - PLoS …, 2016 - journals.plos.org
The phospholipase A2 receptor (PLA2R) is the major target antigen (Ag) in idiopathic
membranous nephropathy (IMN). Recently, several types of immunoassay systems for anti …
membranous nephropathy (IMN). Recently, several types of immunoassay systems for anti …