New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics

J Geddes‐McAlister, RS Shapiro - … of the New York Academy of …, 2019 - Wiley Online Library
Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …

[HTML][HTML] Development and research progress of anti-drug resistant fungal drugs

X Cui, L Wang, Y Lue, C Yue - Journal of Infection and Public Health, 2022 - Elsevier
With the widespread use of immunosuppressive agents and the increase in patients with
severe infections, the incidence of fungal infections worldwide has increased year by year …

Novel agents and drug targets to meet the challenges of resistant fungi

MW McCarthy, DP Kontoyiannis… - The Journal of …, 2017 - academic.oup.com
The emergence of drug-resistant fungi poses a major threat to human health. Despite
advances in preventive, diagnostic, and therapeutic interventions, resistant fungal infections …

Antifungal drugs: the current armamentarium and development of new agents

N Robbins, GD Wright, LE Cowen - Microbiology spectrum, 2016 - Am Soc Microbiol
Invasive fungal infections are becoming an increasingly important cause of human mortality
and morbidity, particularly for immunocompromised populations. The fungal pathogens …

Antifungal drug development: challenges, unmet clinical needs, and new approaches

T Roemer, DJ Krysan - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Invasive, life-threatening fungal infections are an important cause of morbidity and mortality,
particularly for patients with compromised immune function. The number of therapeutic …

Potential targets for the development of new antifungal drugs

H Su, L Han, X Huang - The journal of antibiotics, 2018 - nature.com
In recent years, incidences of invasive fungal infections have greatly increased, especially in
immunosuppressed patients, but most today's antifungal drugs are not completely effective …

Antifungal drug discovery: something old and something new

A Butts, DJ Krysan - 2012 - journals.plos.org
Invasive fungal infections are devastating. Despite state-of-theart antifungal therapy, the
mortality rates for invasive infections with the three most common species of human fungal …

Invasive fungal infections: problems and challenges for developing new antifungal compounds

TJ Walsh - Emerging Targets in Antibacterial and Antifungal …, 1992 - Springer
Invasive fungal infections have emerged during the past two decades as important
pathogens causing formidable morbidity and mortality in an increasingly diverse and …

[HTML][HTML] Fungal infections: Pathogenesis, antifungals and alternate treatment approaches

GKK Reddy, AR Padmavathi… - Current Research in …, 2022 - Elsevier
Increasing incidence of fungal infections of recent times requires immediate intervention.
Fungal infections are seldom construed at initial stages that intensify the severity of …

Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium

A Arastehfar, T Gabaldón, R Garcia-Rubio, JD Jenks… - Antibiotics, 2020 - mdpi.com
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …