Sepsis is an unusual systemic infection caused by bacteria, which is a life-threatening organ
dysfunction. The innate immune system plays an important role in this process; however, the …

Neutrophils and T lymphocytes are closely related to occurrence of immunosuppression in
sepsis. Studies have shown that neutrophil apoptosis decreases and T lymphocyte …

Abstract Background Neutrophil extracellular traps (NETs) are involved in the development
of sepsis-induced acute respiratory distress syndrome (ARDS). Glycyrrhizin (GL), the main …

Sepsis is a multiple organ dysfunction syndrome due to a dysregulated response to infection
with unacceptably high mortality. Currently, no effective treatment exists for sepsis …

Septic shock leads to myocardial dysfunction and induces inflammation. Nod-like receptor
family pyrin domain-containing 3 (NLRP3) inflammasomes are involved in inflammation, and …

Background Acute kidney injury is a common and severe complication of sepsis. Sepsis-
induced acute kidney injury (S-AKI) is an independent risk factor for mortality among sepsis …

Septic shock is defined as a subset of sepsis, which is associated with a considerably high
mortality risk. The caspase-11 non-canonical inflammasome is sensed and activated by …

The NLRP3 inflammasome functions as an inflammatory driver, but its relationship with lipid
metabolic changes in early sepsis remains unclear. Here, we found that GITR expression in …

Sepsis is the leading cause of death among critically ill patients and natural killer T (NKT)
cell activation is essential to induce inflammatory cytokine cascade in sepsis. However, little …

Acute lung injury (ALI), a severe and life-threatening inflammation of the lung, with high
morbidity and mortality, underscoring the urgent need for novel treatments. Ge-Gen-Qin-Lian …