Ferroptotic cell death: new regulatory mechanisms for metabolic diseases

Y Le, Z Zhang, C Wang, D Lu - Endocrine, Metabolic & Immune …, 2021 - ingentaconnect.com
Background: Cell death is a fundamental biological phenomenon that contributes to the
pathogenesis of various diseases. Regulation of iron and iron metabolism has received …

The role of ferroptosis in metabolic diseases

L Xie, B Fang, C Zhang - Biochimica et Biophysica Acta (BBA)-molecular …, 2023 - Elsevier
The annual incidence of metabolic diseases such as diabetes, non-alcoholic fatty liver
disease (NAFLD), osteoporosis, and atherosclerosis (AS) is increasing, resulting in a heavy …

Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases

Y Yu, Y Yan, F Niu, Y Wang, X Chen, G Su, Y Liu… - Cell death …, 2021 - nature.com
Ferroptosis, a recently identified and iron-dependent cell death, differs from other cell death
such as apoptosis, necroptosis, pyroptosis, and autophagy-dependent cell death. This form …

Ferroptosis and its potential role in metabolic diseases: a curse or revitalization?

JY Duan, X Lin, F Xu, SK Shan, B Guo… - Frontiers in Cell and …, 2021 - frontiersin.org
Ferroptosis is classified as an iron-dependent form of regulated cell death (RCD) attributed
to the accumulation of lipid hydroperoxides and redox imbalance. In recent years …

Ferroptosis: a potential target in cardiovascular disease

Y Leng, X Luo, J Yu, H Jia, B Yu - Frontiers in Cell and …, 2022 - frontiersin.org
Ferroptosis is a new form of regulatory cell death characterized by iron-dependent and
intracellular lipid peroxidation. Ferroptosis can be divided into two stages. The first stage is …

[HTML][HTML] Emerging regulatory mechanisms in cardiovascular disease: Ferroptosis

S Jin, H Wang, X Zhang, M Song, B Liu… - Biomedicine & …, 2024 - Elsevier
Ferroptosis, distinct from apoptosis, necrosis, autophagy, and other types of cell death, is a
novel iron-dependent regulated cell death characterized by the accumulation of lipid …

The emerging role of ferroptosis in cardiovascular diseases

M Hong, J Rong, X Tao, Y Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
Ferroptosis is one type of programmed cell death discovered in recent years, which is
characterized by iron-dependent lipid peroxidation and participating in iron, lipid and …

Molecular mechanisms of ferroptosis in cardiovascular disease

Q Zeng, T Jiang - Molecular and Cellular Biochemistry, 2024 - Springer
Ferroptosis is a newly recognized type of regulated cell death that is characterized by the
accumulation of iron and lipid peroxides in cells. Studies have shown that ferroptosis plays a …

Ferroptosis mechanisms and regulations in cardiovascular diseases in the past, present, and future

W Fang, S Xie, W Deng - Cell Biology and Toxicology, 2024 - Springer
Cardiovascular diseases (CVDs) are the main diseases that endanger human health, and
their risk factors contribute to high morbidity and a high rate of hospitalization. Cell death is …

The link between ferroptosis and cardiovascular diseases: a novel target for treatment

H Hu, Y Chen, L Jing, C Zhai, L Shen - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Ferroptosis is an iron-dependent cell death, which is characterized by iron overload and
lipid peroxidation. Ferroptosis is distinct from apoptosis, necroptosis, autophagy, and other …