Objectives. Gap junctional intercellular communication (GJIC) is believed to play an
important role in the maintenance of cell homeostasis, and its disruption may be associated …

Gap junctional intercellular communications (GJIC) are known as the channels for the direct
transfer of cytoplasmic molecules between neighboring cells and are lost during …

Gap junction intercellular communication (GJIC) is considered to play roles in regulation of
homeostasis, development and differentiation of many tissues. In the present study, using …

Connexins make up a gene family encoding proteins that form intercellular channels known
as gap junctions. Decreases in connexin expression and loss of intercellular communication …

Many reports have suggested that gap junctional intercellular communication or gap
junction proteins (connexins) could have tumor suppression characteristics. We investigated …

Modulation of gap junctional intercellular communication (GJIC) was studied in a multistep
model of human renal epithelial carcinogenesis. We report that the majority of primary …

The loss of homeostasis which characterizes tumor growth is probably the result of a
deregulated intercellular communication capacity of the cancer cells. The deregulation of …

Background Colorectal cancer is one of the most common cancers in the United States with
an early detection rate of only 39%. Colorectal cancer cells along with other cancer cells …

BACKGROUND Gap junctional communication (GJC) has been implicated in the control of
cell proliferation. Numerous cancer cells show a decrease or loss of GJC compared to their …

A considerable amount of evidence has established that gap junctional intercellular
communication (GJIC) suppresses tumor development by halting the stage of tumor …