[HTML][HTML] Signal transduction of gap junctional genes, connexin32, connexin43 in human hepatocarcinogenesis

XD Ma, X Ma, YF Sui, WL Wang… - World Journal of …, 2003 - ncbi.nlm.nih.gov
AIM: To investigate gap junctional intercellular communication (GJIC) in hepatocellular
carcinoma cell lines, and signal transduction mechanism of gap junction genes connexin32 …

Frequent reduction of gap junctional intercellular communication and connexin43 expression in human and mouse lung carcinoma cells.

K Cesen-Cummings, MJ Fernstrom… - …, 1998 - academic.oup.com
The reduced gap junctional intercellular communication (GJIC) and gap junction protein
(connexin) expression that have been noted in many neoplastic cell types may contribute to …

Role of connexin (gap junction) genes in cell growth control and carcinogenesis

H Yamasaki, V Krutovskikh, M Mesnil, T Tanaka… - Comptes Rendus de l' …, 1999 - Elsevier
Gap junctional intercellular communication (GJIC) is considered to play a key role in the
maintenance of tissue independence and homeostasis in multicellular organisms by …

[HTML][HTML] Defective gap junctional intercellular communication in the carcinogenic process

M Mesnil, S Crespin, JL Avanzo… - Biochimica et Biophysica …, 2005 - Elsevier
Gap junctions are membrane structures made of intercellular channels which permit the
diffusion from cytoplasm to cytoplasm of small hydrophilic molecules. Nearly 40 years ago …

Enhancement of liver cell gap junction protein expression by glucocorticoids

P Ren, AW de Feijter, DL Paul, RJ Ruch - Carcinogenesis, 1994 - academic.oup.com
Gap junctional intercellular communication (GJIC) and the expression of gap junction
proteins (connexins) may be involved in growth regulation and neoplastic transformation …

Connexin 43 reverses malignant phenotypes of glioma stem cells by modulating E-cadherin

SC Yu, HL Xiao, XF Jiang, QL Wang, Y Li, XJ Yang… - Stem Cells, 2012 - academic.oup.com
Malfunctioned gap junctional intercellular communication (GJIC) has been thought
associated with malignant transformation of normal cells. However, the role of GJIC-related …

Aberrant expression of gap junction gene in primary human hepatocellular carcinomas: Increased expression of cardiac‐type gap junction gene connexin 43

M Oyamada, VA Krutovskikh, M Mesnil… - Molecular …, 1990 - Wiley Online Library
The expression of connexin 32 (the major liver gap junction protein) and connexin 43 (the
major cardiac gap junction protein) was examined in six surgically removed human …

[HTML][HTML] Roles of gap junctions and connexins in non-neoplastic pathological processes in which cell proliferation is involved

ML Zaidan Dagli, FJ Hernandez-Blazquez - Journal of membrane biology, 2007 - Springer
Cell proliferation is an important process for reproduction, growth and renewal of living cells
and occurs in several situations during life. Cell proliferation is present in all the steps of …

Gap junction protein connexin43 deregulation contributes to bladder carcinogenesis via targeting MAPK pathway

X Ai, Q Chi, Y Qiu, H Li, D Li, J Wang… - Molecular and cellular …, 2017 - Springer
High expression of connexins was found in a variety of cancers, but their role is still
controversial. We investigated whether connexin43 (Cx43) contributed to bladder …

Gap junction intercellular communication propagates cell death in cancerous cells

VA Krutovskikh, C Piccoli, H Yamasaki - Oncogene, 2002 - nature.com
Gap junction intercellular communication (GJIC) or cell coupling has an important function in
maintaining tissue homeostasis and is thus a critical factor in the life and death balance of …