Decrease in connexin (Cx) expression and loss of gap junctional intercellular
communication (GJIC) have been associated with aberrant cell growth and enhanced …

The aetiopathogenesis of urinary bladder tumours in cattle involves prolonged ingestion of
bracken fern and infection by bovine papillomavirus types 1 or 2 (BPV-1/2). The oncogenic …

Background Gap junctional intercellular communication is thought to play an important role
in the maintenance of cell differentiation and homeostasis. Gap junctions connect …

Gap junctional intercellular communication (GJIC) maintains normal growth and
differentiation of cells in a tissue. The intercellular molecules traversing gap junctions are …

It has long been known that the gap junction is down-regulated in many tumours. One of the
downregulation mechanisms is the translocation of connexin, a gap junction protein, from …

To develop a strategy for efficacious intervention in order to prevent or treat various cancers,
one must understand the basic mechanism (s) by which various anticancer dietary factors …

Purpose: Gap junctions composed of connexin proteins have an essential role in
intercellular communication and differentiation. Dysregulation of connexin expression is …

Numerous studies have demonstrated a correlation between dysregulation/loss of connexin
expression or gap junction intercellular communication (GJIC) function and decreased …

The idea that the gap junction family of proteins, connexins, are tumour suppressors has
been widely supported through numerous cancer models. However, the paradigm that …

Animal tumor models have demonstrated a close correlation between gap junctional,
intercellular communication (GJIC) and tumor metastasis. To examine GJIC levels in human …