Easily Accessible Auxiliary for Palladium‐Catalyzed Intramolecular Amination of C(sp2)H and C(sp3)H Bonds at δ‐ and ε‐Positions
An easily synthesized and accessible N, O‐bidentate auxiliary has been developed for
selective C H activation under palladium catalysis. The novel auxiliary showed its first …
selective C H activation under palladium catalysis. The novel auxiliary showed its first …
Ligand‐Promoted ortho‐CH Amination with Pd Catalysts
Abstract 2, 4, 6‐Trimethoxypyridine is identified as an efficient ligand for promoting a Pd‐
catalyzed ortho‐C H amination of both benzamides and triflyl‐protected benzylamines …
catalyzed ortho‐C H amination of both benzamides and triflyl‐protected benzylamines …
Palladium-catalyzed intermolecular amination of unactivated C (sp 3)–H bonds via a cleavable directing group
L Jin, X Zeng, S Li, X Hong, G Qiu, P Liu - Chemical Communications, 2017 - pubs.rsc.org
Palladium-catalyzed intermolecular amination of unactivated C (sp3)–H bonds was
developed. Using NFSI as both the amino source and the oxidant, this protocol operates …
developed. Using NFSI as both the amino source and the oxidant, this protocol operates …
Palladium(0)/PAr3‐Catalyzed Intermolecular Amination of C(sp3)H Bonds: Synthesis of β‐Amino Acids
An intermolecular C (sp3) H amination using a Pd0/PAr3 catalyst was developed. The
reaction begins with oxidative addition of R2N OBz to a Pd0/PAr3 catalyst and subsequent …
reaction begins with oxidative addition of R2N OBz to a Pd0/PAr3 catalyst and subsequent …
Palladium-Catalyzed C–H Amination of C(sp2) and C(sp3)–H Bonds: Mechanism and Scope for N-Based Molecule Synthesis
YN Timsina, BF Gupton, KC Ellis - ACS Catalysis, 2018 - ACS Publications
Nitrogen-containing compounds are the most common structural architectures in drug
candidates, natural and biological products, and small-molecule therapeutics. Within the …
candidates, natural and biological products, and small-molecule therapeutics. Within the …
Palladium(0)‐Catalyzed Intermolecular Amination of Unactivated CH Bonds
J Pan, M Su, SL Buchwald - Angewandte Chemie, 2011 - infona.pl
Auf die eine oder andere Weise: Die Titelreaktion nichtaktivierter C sp 3‐H‐Bindungen mit
Arylaminen wird untersucht (siehe Schema; dba= Dibenzylidenaceton, Tf …
Arylaminen wird untersucht (siehe Schema; dba= Dibenzylidenaceton, Tf …
Remote amide-directed palladium-catalyzed benzylic C–H amination with N-fluorobenzenesulfonimide
T Xiong, Y Li, Y Lv, Q Zhang - Chemical communications, 2010 - pubs.rsc.org
An unprecedented remote amide-directed palladium-catalyzed intermolecular highly
selective benzylic C–H amination with N-fluorobenzenesulfonimide is developed, which …
selective benzylic C–H amination with N-fluorobenzenesulfonimide is developed, which …
Readily Removable Directing Group Assisted Chemo‐ and Regioselective C(sp3)H Activation by Palladium Catalysis
Currently used directing groups for selective aliphatic β‐functionalization of carbonyl
compounds show excellent reactivity and selectivity with an amide as a linker. Described …
compounds show excellent reactivity and selectivity with an amide as a linker. Described …
Synthesis of Indolines by Palladium-Catalyzed Intermolecular Amination of Unactivated C(sp3)–H Bonds
X Sun, Z Wu, W Qi, X Ji, C Cheng, Y Zhang - Organic letters, 2019 - ACS Publications
A new palladium-catalyzed C (sp3)–H amination reaction has been developed. 1-(tert-Butyl)-
2-iodobenzene and its derivatives undergo palladium-catalyzed C–H activation to form …
2-iodobenzene and its derivatives undergo palladium-catalyzed C–H activation to form …
Ligand-assisted palladium-catalyzed C–H alkenylation of aliphatic amines for the synthesis of functionalized pyrrolidines
C He, MJ Gaunt - Chemical Science, 2017 - pubs.rsc.org
The development of a ligand-assisted Pd-catalyzed C–H alkenylation of aliphatic amines is
reported. Our studies indicated that an amino-acid-derived ligand renders the C–H bond …
reported. Our studies indicated that an amino-acid-derived ligand renders the C–H bond …