Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States
and incidence rates are rising. Both detection and treatment options for pancreatic cancer …

The tumor microenvironment plays a key role in tumor development and progression.
Stromal cells secrete growth factors, cytokines and extracellular matrix proteins which …

Pancreatic cancer (pancreatic ductal adenocarcinoma (PDAC/PC)) has been an aggressive
disease that is associated with early metastases. It is characterized by dense and …

Background: Pancreatic stellate cells (PSCs, which produce the stroma of pancreatic cancer
(PC)) interact with cancer cells to facilitate PC growth. A candidate growth factor pathway …

It has been more than 25 years since HGF was discovered as a mitogen of hepatocytes.
HGF is produced by stromal cells, and stimulates epithelial cell proliferation, motility …

Hepatocyte growth factor (HGF), also known as scatter factor (SF), plays an important role in
cell: cell adhesion, cell proliferation, motility, and invasiveness of epithelial cells and tumor …

Hepatocyte growth factor plays multiple roles in cancer, by acting as a motility and invasion
stimulating factor, promoting metastasis and tumour growth. Furthermore, it acts as a …

Hepatocyte growth factor (HGF) is a widely expressed growth factor secreted by cells of
mesenchymal origin, which has been shown to be involved in growth processes of multiple …

Hepatocyte growth factor (HGF) and it's receptor, cMET, have become the focus on intense
scrutiny since its discovery in the late 1980s [1, 2] as regards it role in cancer. HGF is now …

Hepatocyte growth factor (HGF) has an important role not only in liver regeneration buy also
in the development of cancer metastasis. It has been known that HGF and its receptor/c-MET …