[HTML][HTML] Molecular and cellular insights into the development of uterine fibroids
Uterine leiomyomas represent the most common benign gynecologic tumor. These hormone-
dependent smooth-muscle formations occur with an estimated prevalence of~ 70% among …
dependent smooth-muscle formations occur with an estimated prevalence of~ 70% among …
Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth
AE Commandeur, AK Styer… - Human Reproduction …, 2015 - academic.oup.com
BACKGROUND Uterine leiomyomas (fibroids) are highly prevalent benign smooth muscle
tumors of the uterus. In the USA, the lifetime risk for women developing uterine leiomyomas …
tumors of the uterus. In the USA, the lifetime risk for women developing uterine leiomyomas …
Uterine fibroids: hiding in plain sight
EA Stewart, RA Nowak - Physiology, 2022 - journals.physiology.org
Uterine fibroids (leiomyomas) are present in> 75% of women and can cause serious
morbidity. They are by far the leading cause of hysterectomy. Fibroids are a complex mixture …
morbidity. They are by far the leading cause of hysterectomy. Fibroids are a complex mixture …
[HTML][HTML] Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management
DK Taylor, K Holthouser, JH Segars, PC Leppert - F1000Research, 2015 - ncbi.nlm.nih.gov
Uterine leiomyomas (fibroids) are the most prevalent medical problem of the female
reproductive tract, but there are few non-surgical treatment options. Although many …
reproductive tract, but there are few non-surgical treatment options. Although many …
Future directions in myoma research
PK Brahma, KM Martel… - … and Gynecology Clinics, 2006 - obgyn.theclinics.com
Our knowledge regarding the pathogenesis, genetics, and improved treatment of uterine
fibroids has expanded exponentially over the past decade. Science is poised for exciting …
fibroids has expanded exponentially over the past decade. Science is poised for exciting …
Epigenomic and enhancer dysregulation in uterine leiomyomas
OW Mlodawska, P Saini, JB Parker… - Human …, 2022 - academic.oup.com
BACKGROUND Uterine leiomyomas, also known as uterine fibroids or myomas, are the
most common benign gynecological tumors and are found in women of reproductive and …
most common benign gynecological tumors and are found in women of reproductive and …
[HTML][HTML] Pathogenomics of uterine fibroids development
VS Baranov, NS Osinovskaya… - International journal of …, 2019 - mdpi.com
We review recent studies dealing with the molecular genetics and basic results of omics
analysis of uterine leiomyoma (LM)—a common benign muscle tumor of the uterus. Whole …
analysis of uterine leiomyoma (LM)—a common benign muscle tumor of the uterus. Whole …
Epigenetic and genetic landscape of uterine leiomyomas: a current view over a common gynecological disease
Purpose Despite the numerous studies on the factors involved in the genesis and growth of
uterine leiomyomas, the pathogenesis of these tumors remains unknown. Intrinsic …
uterine leiomyomas, the pathogenesis of these tumors remains unknown. Intrinsic …
Recent advances in uterine fibroid etiology
MM McWilliams… - Seminars in reproductive …, 2017 - thieme-connect.com
Uterine fibroids, also known as uterine leiomyoma (UL), are monoclonal tumors of the
smooth muscle tissue layer (myometrium) of the uterus. Although ULs are considered …
smooth muscle tissue layer (myometrium) of the uterus. Although ULs are considered …
[HTML][HTML] Molecular insights in uterine leiomyosarcoma: a systematic review
R Sparić, M Andjić, I Babović, L Nejković… - International Journal of …, 2022 - mdpi.com
Uterine fibroids (UFs) are the most common benign tumors of female genital diseases,
unlike uterine leiomyosarcoma (LMS), a rare and aggressive uterine cancer. This narrative …
unlike uterine leiomyosarcoma (LMS), a rare and aggressive uterine cancer. This narrative …