A growing body of evidence indicates that cardiac regeneration after myocardial infarction
can be achieved by stimulating the endogenous capacity of cardiomyocytes (CMs) to …

Developing new therapeutic strategies which could enhance cardiomyocyte regenerative
capacity is of significant clinical importance. Though promising, methods to promote cardiac …

The human heart has a limited capacity to regenerate lost or damaged cardiomyocytes after
cardiac insult. Instead, myocardial injury is characterized by extensive cardiac remodeling …

Mounting evidence over the last few years has indicated that the rate of cardiomyocyte
proliferation, and thus the extent of cardiac renewal, is under the control of the microRNA …

microRNAs are post-transcriptional regulators of gene expression that have been shown to
be central players in the establishment of cellular programs, often acting as switches that …

Cardiovascular diseases are currently the main cause of morbidity and mortality worldwide.
Ischemic heart disease, in particular, is responsible for the majority of cardiac-related …

MicroRNAs (miRNAs) are small noncoding RNAs that block translation or induce
degradation of mRNA and thereby control patterns of gene expression. Acute myocardial …

The adult heart has a limited capacity to replace or regenerate damaged cardiac tissue
following severe myocardial injury. Thus, therapies facilitating the induction of cardiac …

MicroRNAs are small non-coding post-translational biomolecules which, when expressed,
modify their target genes. It is estimated that microRNAs regulate production of …

The progressive appreciation that multiple types of RNAs regulate virtually all aspects of
tissue function and the availability of effective tools to deliver RNAs in vivo now offers …