Chemokine and cytokine cascade caused by skewing of the Th1‐Th2 balance is associated with high intracranial pressure in HIV‐associated cryptococcal meningitis

L Xu, Y Guo, Y Zhao, Y Xu, X Peng… - Mediators of …, 2019 - Wiley Online Library
Purpose. Serum cytokines/chemokines play important roles in cryptococcal meningitis, but it
is unclear whether cytokines/chemokines in cerebrospinal fluid (CSF) contribute to high …

Cerebrospinal fluid cytokine and chemokine patterns correlate with prognosis of HIV-uninfected cryptococcal meningitis: A prospective observational study

YK Jiang, RY Wang, LH Zhou, JH Cheng… - Frontiers in …, 2022 - frontiersin.org
The cerebrospinal fluid (CSF) immune responses in HIV-uninfected cryptococcal meningitis
(CM) have not been well studied. In this study, we aimed to explore the phenotype of CSF …

Differences in cytokine and chemokine profiles in cerebrospinal fluid caused by the etiology of cryptococcal meningitis and tuberculous meningitis in HIV patients

L Xu, Y Xu, Y Zheng, X Peng, Z Yang… - Clinical & …, 2021 - academic.oup.com
The roles of cytokines and chemokines in HIV-associated cryptococcal meningitis (HCM)
and HIV-associated tuberculous meningitis (HTBM) are debatable. In sum, 34 HIV-infected …

Cerebrospinal fluid cytokine profiles predict risk of early mortality and immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis

JN Jarvis, G Meintjes, T Bicanic, V Buffa… - PLoS …, 2015 - journals.plos.org
Understanding the host immune response during cryptococcal meningitis (CM) is of critical
importance for the development of immunomodulatory therapies. We profiled the …

Cytokine patterns in a prospective cohort of HIV-infected patients with cryptococcal meningitis following initiation of antifungal and antiretroviral therapy

DJ Mora, K Ferreira-Paim, LE Andrade-Silva… - PLoS …, 2017 - journals.plos.org
Cryptococcal meningitis (CM) is a life-threatening infection in HIV-infected patients,
especially in resource-limited settings. Cytokine patterns in the cerebrospinal fluid (CSF) …

A preliminary study on the characteristics of Th1/Th2 immune response in cerebrospinal fluid of AIDS patients with cryptococcal meningitis

A Li, W Zhu, J Yin, X Huang, L Sun, W Hua… - BMC Infectious …, 2021 - Springer
Abstract Background Cryptococcal Meningitis (CM) is a common opportunistic infection in
the late stage of acquired immunodeficiency syndrome (AIDS). Despite the wide use of …

Cytokine profiles at admission can be related to outcome in AIDS patients with cryptococcal meningitis

DJ Mora, LR Fortunato, LE Andrade-Silva… - PloS one, 2015 - journals.plos.org
Cryptococcal meningitis (CM) remains as common life-threatening AIDS-defining illness
mainly in resource-limited settings. Previous reports suggested that baseline cytokine …

Correlation between blood and CSF compartment cytokines and chemokines in subjects with cryptococcal meningitis

EC Okafor, KH Hullsiek, DA Williams… - Mediators of …, 2020 - Wiley Online Library
Background. Though peripheral blood is a crucial sample to study immunology, it is unclear
whether the immune environment in the peripheral vasculature correlates with that at the …

Immune mediators in cerebrospinal fluid during cryptococcosis are influenced by meningeal involvement and human immunodeficiency virus serostatus

O Lortholary, F Dromer… - The Journal of …, 2001 - academic.oup.com
Pro-and anti-inflammatory mediators (tumor necrosis factor [TNF]—α, interleukin [IL]—6, IL-8,
IL-10, and soluble TNF receptor II [sTNFR] II) were measured in cerebrospinal fluid (CSF) …

Different characteristics of cryptococcal meningitis between HIV-infected and HIV-uninfected patients in the Southwest of China

Y Liu, M Kang, SY Wu, Y Ma, ZX Chen, Y Xie… - Medical …, 2017 - academic.oup.com
Cryptococcus is the major pathogen that causes fungal meningitis. In the People's Republic
of China, especially in the Southwest area, cryptococcal meningitis (CM) in HIV-uninfected …