Background and objectives Chronic widespread musculoskeletal pain (CWP) is a symptom
of fibromyalgia and a complex trait with poorly understood pathogenesis. CWP is heritable …

Background and objectives Chronic widespread pain (CWP) is a common disorder
affecting∼ 10% of the general population and has an estimated heritability of 48–52%. In …

Fibromyalgia (FM) is a highly disabling syndrome defined by a low pain threshold and a
permanent state of pain. The mechanisms explaining this complex disorder remain unclear …

Objective Fibromyalgia (FM) represents a complex disorder that is characterized by
widespread pain and tenderness and is frequently accompanied by additional somatic and …

Fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain disorder affecting 2% to 5%
of the general population. Both genetic and environmental factors may be involved. To …

Objective Familial aggregation of fibromyalgia has been increasingly recognized. The goal
of this study was to conduct a genome‐wide linkage scan to identify susceptibility loci for …

Fibromyalgia is a disease characterized by chronic widespread pain with additional
symptoms, such as joint stiffness, fatigue, sleep disturbance, cognitive dysfunction, and …

Objective Many studies suggest a strong familial component to fibromyalgia (FM). However,
those studies have nearly all been confined to individuals with primary FM, ie, FM without …

Fibromyalgia syndrome (FMS), a condition characterized by chronic widespread pain and
tenderness, is a complex condition considered to represent a paradigm of centralized pain …

Fibromyalgia is a chronic disorder characterized by widespread pain and by several non-
pain symptoms. Autoimmunity, small fiber neuropathy and neuroinflammation have been …