System Analysis Based on Pancreatic Cancer Progression Identifies BRINP2 as a Novel Prognostic Biomarker

Y Kang, X Xu, J Liu - Critical Reviews™ in Eukaryotic Gene …, 2023 - dl.begellhouse.com
Pancreatic adenocarcinoma (PAAD) is a malignant tumor of the digestive system, which
develops rapidly and has no obvious early symptoms. This study aims to discover the …

Identification of a nine-gene signature and establishment of a prognostic nomogram predicting overall survival of pancreatic cancer

M Wu, X Li, T Zhang, Z Liu, Y Zhao - Frontiers in oncology, 2019 - frontiersin.org
Background: Pancreatic cancer is highly lethal and aggressive with increasing trend of
mortality in both genders. An effective prediction model is needed to assess prognosis of …

Importance of gene expression signatures in pancreatic cancer prognosis and the establishment of a prediction model

X Yan, H Wan, X Hao, T Lan, W Li, L Xu… - Cancer management …, 2018 - Taylor & Francis
Background and aim Pancreatic cancer (PC) is one of the most common tumors with a poor
prognosis. The current American Joint Committee on Cancer (AJCC) staging system, based …

[HTML][HTML] Identification of hub genes correlated with the pathogenesis and prognosis in Pancreatic adenocarcinoma on bioinformatics methods

LE Shi, X Shang, KC Nie, ZQ Lin, M Wang… - Translational Cancer …, 2020 - ncbi.nlm.nih.gov
Background Pancreatic adenocarcinoma (PC), is a type of digestive tract cancer with the
highest mortality all over the word, and its exact pathogenesis is not clear. Therefore, it is of …

RETRACTED ARTICLE: Uncovering the pathogenesis and identifying novel targets of pancreatic cancer using bioinformatics approach

LL Zhao, T Zhang, LW Zhuang, BZ Yan, RF Wang… - Molecular biology …, 2014 - Springer
Pancreatic cancer is a uniformly lethal disease that can be difficult to diagnose at its early
stage. Thus, our present study aimed to explore the underlying mechanism and identify new …

Machine learning identifies SLC6A14 as a novel biomarker promoting the proliferation and metastasis of pancreatic cancer via Wnt/β-catenin signaling

C Dang, Q Bian, F Wang, H Wang, Z Liang - Scientific Reports, 2024 - nature.com
Pancreatic cancer (PC) has the poorest prognosis compared to other common cancers
because of its aggressive nature, late detection, and resistance to systemic treatment. In this …

Identification of prognostic risk factors for pancreatic cancer using bioinformatics analysis

D Jin, Y Jiao, J Ji, W Jiang, W Ni, Y Wu, R Ni, C Lu… - PeerJ, 2020 - peerj.com
Background Pancreatic cancer is one of the most common malignant cancers worldwide.
Currently, the pathogenesis of pancreatic cancer remains unclear; thus, it is necessary to …

PAC-5 gene expression signature for predicting prognosis of patients with pancreatic adenocarcinoma

J Kim, YH Jo, M Jang, NNY Nguyen, HR Yun, SH Ko… - Cancers, 2019 - mdpi.com
Pancreatic adenocarcinoma (PAC) is one of the most aggressive malignancies.
Intratumoural molecular heterogeneity impedes improvement of the overall survival rate …

[PDF][PDF] Gene signature developed for predicting early relapse and survival in early-stage pancreatic cancer

L Huang, X Yuan, L Zhao, Q Han, H Yan, J Yuan… - BJS open, 2023 - academic.oup.com
Background The aim of this study was to construct a predictive signature integrating tumour-
mutation-and copy-number-variation-associated features using machine learning to …

Prognostic assessment capability of a five-gene signature in pancreatic cancer: a machine learning based-study

X Zhang, L Yang, D Zhang, X Wang, X Bu, X Zhang… - BMC …, 2023 - Springer
Background A prognostic assessment method with good sensitivity and specificity plays an
important role in the treatment of pancreatic cancer patients. Finding a way to evaluate the …