[HTML][HTML] Identification of a novel cell cycle-related risk signature predicting prognosis in patients with pancreatic adenocarcinoma

D Xu, R Qin, M Li, J Shen, Y Mao, K Tang, A Zhang… - Medicine, 2022 - journals.lww.com
Background: Growing evidence have indicated that cell cycle-related genes (CRGs) play an
essential role in the progression of pancreatic adenocarcinoma (PAAD). Nevertheless, the …

Development and clinical validation of a novel 9-gene prognostic model based on multi-omics in pancreatic adenocarcinoma

D Xu, Y Wang, X Liu, K Zhou, J Wu, J Chen… - Pharmacological …, 2021 - Elsevier
The prognoses of patients with pancreatic adenocarcinoma (PAAD) remain poor due to the
lack of biomarkers for early diagnosis and effective prognosis prediction. RNA sequencing …

Development and validation of prognostic and diagnostic model for pancreatic ductal adenocarcinoma based on scRNA-seq and bulk-seq datasets

K Chen, X Liu, W Liu, F Wang, X Tian… - Human Molecular …, 2022 - academic.oup.com
The 5-year overall survival (OS) of pancreatic ductal adenocarcinoma (PDAC) is only 10%,
partly owing to the lack of reliable diagnostic and prognostic biomarkers. The raw gene-cell …

Therapeutic Target Identification in Pancreatic Ductal Adenocarcinoma: A Comprehensive In-Silico Study employing WGCNA and Trader

P Yavari, Y Masoudi-Sobhanzadeh, A Roointan - 2023 - researchsquare.com
Pancreatic ductal adenocarcinoma (PDAC) is recognized as a highly aggressive fatal
disease accounting for more than 90% of all pancreatic malignancies. Considering the …

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

S Haider, J Wang, A Nagano, A Desai, P Arumugam… - Genome medicine, 2014 - Springer
Background Improved usage of the repertoires of pancreatic ductal adenocarcinoma
(PDAC) profiles is crucially needed to guide the development of predictive and prognostic …

Transcriptome‐wide association study identifies multiple genes and pathways associated with pancreatic cancer

L Gong, D Zhang, Y Lei, Y Qian, X Tan… - Cancer Medicine, 2018 - Wiley Online Library
Aim To identify novel candidate genes for pancreatic cancer. Methods We performed a
transcriptome‐wide association study (TWAS) analysis of pancreatic cancer (PC). GWAS …

Abstract PR07: Transcriptome meta-analysis identifies new 5-gene classifier for early detection of pancreatic cancer

M Bhasin, O Bucur, K Ndebele, J Plati, A Bullock, X Gu… - Cancer Research, 2015 - AACR
Background: Pancreatic ductal adenocarcinoma (PDAC) is a truly devastating disease,
primarily due to late diagnosis when curative resection is no longer possible and the lack of …

[HTML][HTML] Prognostic-related genes for pancreatic cancer typing and immunotherapy response prediction based on single-cell sequencing data and bulk sequencing …

X Wang, S Jiang, X Zhou, X Wang, L Li… - Oncology Research, 2023 - ncbi.nlm.nih.gov
Background Pancreatic cancer is associated with high mortality and is one of the most
aggressive of malignancies, but studies have not fully evaluated its molecular subtypes …

Analysis of immune-related signatures related to CD4+ T cell infiltration with gene co-expression network in pancreatic adenocarcinoma

Z Tan, Y Lei, B Zhang, S Shi, J Liu, X Yu, J Xu… - Frontiers in …, 2021 - frontiersin.org
Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most invasive solid
malignancies. Immunotherapy and targeted therapy confirmed an existing certain curative …

Identification and Interaction Analysis of Molecular Markers in Pancreatic Ductal Adenocarcinoma by Integrated Bioinformatics Analysis and Molecular Docking …

B Vastrad, C Vastrad, A Tengli - medRxiv, 2020 - medrxiv.org
The current investigation aimed to mine therapeutic molecular targets that play an key part in
the advancement of pancreatic ductal adenocarcinoma (PDAC). The expression profiling by …