Intrauterine growth restriction (IUGR) is associated with reduced placental supply of
nutrients to the fetus. Lipoprotein lipase (LPL) mediates the hydrolysis of triglycerides from …

Background Gestational diabetes mellitus (GDM) is associated with adverse pregnancy
outcomes. It is known that GDM is associated with an altered placental function and changes …

Gestational diabetes mellitus (GDM)“program” an elevated risk of metabolic syndrome in the
offspring. Epigenetic alterations are a suspected mechanism. GDM has been associated …

Maternal diabetes and/or obesity in pregnancy are undoubtedly associated with later
disease-risk in the offspring. The placenta, interposed between the mother and the foetus, is …

Maternal hyperglycemia during pregnancy is associated with excess fetal growth and
adverse perinatal and developmental outcomes. Placental epigenetic maladaptation may …

Context: Fetal supply of maternally derived fatty acids requires lipase-mediated hydrolysis of
lipoprotein-borne triglycerides and phospholipids at the placental surface. Objective: The …

Background Birthweight marks an important milestone of health across the lifespan,
including cardiometabolic disease risk in later life. The placenta, a transient organ at the …

Diabetes mellitus (DM) during pregnancy can result in fetal overgrowth, likely due to
placental dysfunction, which has health consequences for the infant. Here we test our …

Advanced maternal age and obesity are the main risk factors to develop gestational
diabetes mellitus (GDM). Obesity is a consequence of the increased storage of …

Gestational diabetes mellitus (GDM) is an important metabolic complication of pregnancy,
which affects the future health of both the mother and the newborn. The pathogenesis of …