Objective: DNA methylation is an important epigenetic regulator of gene transcription, and is
involved in many diseases, which has been researched recently. In this study, we aimed to …

Maternal obesity is associated with adverse outcomes. Placental lipid droplets (LD) have
been implicated in maternal-fetal lipid transfer but it is not known whether placental LD fat …

Aims Gestational diabetes mellitus (GDM) has always been a concerning issue for pregnant
women. In recent studies, GDM was found to be related to epigenetic modifications, which …

Background Fetal exposure to maternal GDM increases offspring risk for adult-onset
metabolic syndromes. Epigenetic modifications such as DNA methylation are modulators for …

Aims/hypothesis Individuals exposed to maternal diabetes in utero are more likely to
develop metabolic and cardiovascular diseases later in life. This may be partially attributable …

OBJECTIVE: Changes in metabolic homeostasis in pregnant diabetic women are potential
determinants of increased adiposity of the fetus. The aim of this study was to characterize …

Epigenetics can be loosely defined as the study of cellular “traits” that influence biological
phenotype in a fashion that is not dependent on the underlying primary DNA sequence. One …

Background Intrauterine exposure to a disturbed maternal glucose metabolism is associated
with adverse offspring outcomes. DNA methylation is a potential mechanism underlying …

Objective Offspring exposed to gestational obesity have an increased risk for chronic
diseases. Increasing evidence suggests that epigenetics may play a mechanistic role in …

Background: Factors determining lipoprotein concentrations in the fetus are not yet fully
understood. We postulated that an important factor is the genetic make-up of the mother. In …