Diabetic foot ulceration results from factors extrinsic to the foot such as repeated trauma,
ischaemia and infection, as well as intrinsic factors that lead to impairment of wound healing …

Background: Diabetic foot ulcers are one of the major causes of mortality in diabetic patients.
Very few drugs and therapies have regulatory approval for this indication and several agents …

Introduction: The number of people with diabetes mellitus (DM) is estimated to exceed 640
million by the year 2040. Diabetic foot ulcer (DFU) is a debilitating illness that affects more …

Diabetic foot ulcers occur in up to 15% of all diabetic patients and are a leading cause of
nontraumatic amputation worldwide. Neuropathy, abnormal foot biomechanics, peripheral …

Background: Diabetic foot ulcer (DFU) is one of the leading complications of type-2 diabetes
mellitus. It is associated with neuropathy and peripheral arterial disease of the lower limb in …

Introduction: Diabetic ulcers are chronic nonhealing ulcerations that despite the available
medical tools still result in high amputation rates. Growing evidence suggests that alteration …

Foot ulcers are one of the main complications in diabetes mellitus, with a 15% life time risk in
all diabetic patients. The problem and features are infection, ulceration, or gangrene …

Introduction: Diabetic foot ulceration is a serious secondary complication of diabetes mellitus
and the most common cause of hospitalization in diabetic patients. The etiology of diabetic …

Diabetic foot ulcers are the most common lower extremity complications of diabetes.
Peripheral neuropathy and peripheral vascular disease are the underlying risk factors for …

The diabetic foot remains a major cause of morbidity worldwide. Even though considerable
progress has been achieved over the past years, there is still an urgent need for …