Aberrations in the complement system have been shown to be direct or indirect
pathophysiological mechanisms in a number of diseases and pathological conditions such …

Complement system aberrations have been identified as pathophysiological mechanisms in
a number of diseases and pathological conditions either directly or indirectly. Examples of …

The complement system plays an important role in varying types of disease, ranging from
inflammatory and autoimmune disorders to immune deficiency states. In addition, new …

Complement immunobiology, and with it complement analysis, has undergone a
renaissance in the past decade. Classically, complement analysis was limited number of …

Complement deficiencies are probably vastly under-diagnosed within clinical medicine.
Judging from a Swedish study of C2 deficiency, a deficiency with an estimated prevalence of …

In recent years, progress in the delineation of reaction mechanisms of the complement
system greatly stimulated studies on the possible significance of complement in clinical …

In recent years, complement analysis of body fluids and biopsies, going far beyond C3 and
C4, has significantly enhanced our understanding of the disease process. Such expanded …

Via its multiple functional activities, the complement system plays a major role in host
defense against infection and in inffammatory processes. The system consists of more than …

Complement deficient cases reported in the second half of the last century have been of
great help in defining the role of complement in host defence. Surveys of the deficient …

The complement system is a complex and autoregulated multistep cascade at the interface
of innate and adaptive immunity. It is activated by immune complexes or apoptotic cells …