Mechanisms of HBV immune evasion
A Kuipery, AJ Gehring, M Isogawa - Antiviral research, 2020 - Elsevier
The concept of immune evasion is a longstanding topic of debate during chronic Hepatitis B
Virus infection. The 292 million individuals chronically infected by HBV are clear evidence …
Virus infection. The 292 million individuals chronically infected by HBV are clear evidence …
Innate immunity and HBV persistence
Hepatitis B virus (HBV) causes chronic infections that are associated with immune
dysfunction. Though T cell impairment is perhaps the most prominent immune change …
dysfunction. Though T cell impairment is perhaps the most prominent immune change …
[HTML][HTML] Crosstalk between innate and adaptive immunity in hepatitis B virus infection
L Wang, K Wang, ZQ Zou - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) infection is a major public health problem worldwide. HBV is not
directly cytotoxic to infected hepatocytes; the clinical outcome of infection results from …
directly cytotoxic to infected hepatocytes; the clinical outcome of infection results from …
[HTML][HTML] HBV-specific adaptive immunity
The successful control of HBV infection requires an efficient expansion of distinct elements
of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the …
of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the …
The host–pathogen interaction during HBV infection: immunological controversies
A Bertoletti, MK Maini, C Ferrari - Antiviral therapy, 2010 - journals.sagepub.com
HBV is a hepatotropic and non-cytopathic virus that causes more than one million deaths
annually from liver cirrhosis and hepatocellular carcinoma. As the virus itself is non …
annually from liver cirrhosis and hepatocellular carcinoma. As the virus itself is non …
[HTML][HTML] Innate immune targets of hepatitis B virus infection
ZQ Zou, L Wang, K Wang, JG Yu - World journal of hepatology, 2016 - ncbi.nlm.nih.gov
Approximately 400 million people are chronically infected with hepatitis B virus (HBV)
globally despite the widespread immunization of HBV vaccine and the development of …
globally despite the widespread immunization of HBV vaccine and the development of …
[HTML][HTML] Innate antiviral immune responses to hepatitis B virus
M Ait-Goughoulte, J Lucifora, F Zoulim, D Durantel - Viruses, 2010 - mdpi.com
Hepatitis B virus (HBV) is a major cause of acute and chronic hepatitis in humans. As HBV
itself is currently viewed as a non-cytopathic virus, the liver pathology associated with …
itself is currently viewed as a non-cytopathic virus, the liver pathology associated with …
Host–virus interactions in hepatitis B virus infection
LG Guidotti, M Isogawa, FV Chisari - Current opinion in immunology, 2015 - Elsevier
Highlights•Hepatocellular HBV infection is noncytopathic.•HBV does not induce a
measurable innate immune response in vivo.•Robust, broad adaptive immune responses …
measurable innate immune response in vivo.•Robust, broad adaptive immune responses …
[HTML][HTML] Innate immune responses in hepatitis B virus (HBV) infection
A Busca, A Kumar - Virology journal, 2014 - Springer
Hepatitis B virus (HBV) infection has a low rate of chronicity compared to HCV infection, but
chronic liver inflammation can evolve to life threatening complications. Experimental data …
chronic liver inflammation can evolve to life threatening complications. Experimental data …
Republished: Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
A Bertoletti, C Ferrari - Postgraduate Medical Journal, 2013 - academic.oup.com
Abstract Knowledge of the immunological events necessary to control hepatitis B virus
(HBV) infection has accelerated in recent years, but their translation towards therapeutic …
(HBV) infection has accelerated in recent years, but their translation towards therapeutic …