Liposomes have been extensively explored as drug carriers, but their clinical translation has
been hampered by their low drug-loading content and premature leakage of drug payloads …

Active targeting and precise control of drug release based on nanoparticle therapies are
urgently required to precisely treat cancer. We have custom-synthesized a functional lipid …

Liposomes have proven to be effective nanocarriers due to their ability to encapsulate and
deliver a wide variety of therapeutic cargo. A key goal of liposome research is to enhance …

Formation of an occlusive thrombus is a critical pathophysiological feature of numerous
cardiovascular diseases. Thrombosis is promoted by P‐selectin overexpressed on activated …

Rapid cut‐off of blood supply in diseases involving thrombosis is a major cause of morbidity
and mortality worldwide. However, the current thrombolysis strategies offer limited results …

Due to the high morbidity and mortality of cardiovascular diseases, there is an urgent need
for research on antithrombotic strategies. In view of the short half-life, insufficient drug …

The goal of the present work was to design and test an acute-use nanoparticle-based
antithrombotic agent that exhibits sustained local inhibition of thrombin without requiring a …

Thrombosis is a principle cause of various life-threatening cardiovascular diseases.
However, current antithrombotic treatments using drugs only offer limited efficacy due to …

All trans-retinoic acid (atRA) has potent anti-inflammatory and antiplatelet activity, but its
clinical translation as an antithrombotic drug has been hampered by its low therapeutic …

Systemic thrombolytic drug administration has always gained an unideal therapeutic effect
due to the rapid neutralization by its antidotes. It is significant to seek an approach for …