Recent work has contributed to understanding of the physiology of the brain endothelial
cells forming the blood–brain barrier (BBB), and their interaction with the associated cells of …

The blood-brain barrier (BBB) is a highly specialized structural and biochemical barrier that
regulates the entry of blood-borne molecules into brain, and preserves ionic homeostasis …

The microvasculature of the brain forms a protective blood-brain barrier (BBB) that ensures a
homeostatic environment for the central nervous system (CNS), which is essential for …

The delivery of many potentially therapeutic and diagnostic compounds to specific areas of
the brain is restricted by brain barriers, of which the most well known are the blood–brain …

The blood–brain barrier (BBB) is a dynamic and complex interface between blood and the
central nervous system that strictly controls the exchanges between the blood and brain …

The blood–brain barrier (BBB) is a diffusion barrier, which impedes influx of most
compounds from blood to brain. Three cellular elements of the brain microvasculature …

Neural survival and signaling within the CNS require a highly controlled microenvironment
that depends on the normal function of a neurovascular unit, which includes several …

Neural signalling within the central nervous system (CNS) requires a highly controlled
microenvironment. Cells at three key interfaces form barriers between the blood and the …

The notion that a static blood–brain barrier (BBB) controls the rapidly changing brain
environment is obsolete. Not only have we recognized the role of the BBB in maintenance of …

The blood-brain barrier (BBB) is a fundamental component of the central nervous system
(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain …