Intracellular calcium ion concentration ([Ca2+] i) transients are observed in the fertilized
eggs of all species investigated so far, and are critical for initiating several events related to …

The generation of calcium oscillations at fertilisation and during mitosis appears to be
controlled by the cell cycle machinery. For example, the calcium oscillations in oocytes and …

We have investigated the relationship between the sperm-triggered Ca2+ oscillations and
the activities of two cell cycle kinases (MPF activity and MAP kinase activity) at fertilisation of …

Fertilisation in ascidians triggers a series of periodic rises in cytosolic Ca2+ that are
essential for release from metaphase I arrest and progression through meiosis II. These …

Sperm-triggered Ca2+ oscillations occur throughout the animal kingdom. The mechanism
sperm use to trigger Ca2+ oscillations at fertilization has not been resolved in any egg. The …

Changes in [Ca2+] iare an essential factor regulating egg activation. Matured ascidian eggs
are arrested at metaphase I, and two series of [Ca2+] itransients have been observed after …

In ascidians the cell cycle machinery has been studied mainly in oocytes while ascidian
embryos have been used to dissect the mechanism that controls asymmetric cell division …

The fertilising sperm triggers a transient Ca2+ increase that releases eggs from cell cycle
arrest in the vast majority of animal eggs. In vertebrate eggs, Erp1, an APC/Ccdc20 inhibitor …

The egg of ascidians (urochordate), as virtually all animal and plant species, displays Ca2+
signals upon fertilisation. These Ca2+ signals are repetitive Ca2+ waves that initiate in the …

Background: Internal calcium waves and oscillations are now recognized as universal
features of cellular activation, but their exact role remains uncertain. In mammalian and …