Purpose To investigate the increasing prevalence of colistin resistance in animal
Escherichia coli isolates and their mcr-1-carrying plasmids, especially those shared by …

Abstract Objectives In November 2015, a plasmid-mediated colistin resistance, MCR-1, was
described in animals, food and humans in China, and it was considered as a potential …

Background: Antimicrobial resistance is a serious public-health problem throughout the
world. Escherichia coli, the most common Gram-negative microorganism, has developed …

The emergence and dissemination of colistin resistance in Enterobacteriaceae mediated by
plasmid-borne mcr genes in recent years now pose a threat to public health. In this study, we …

Considering the serious threat to food safety and public health posed by pathogens with
colistin resistance, colistin was banned as a growth promoter in 2017 in China. In recent …

Background mcr-1-positive Escherichia coli has emerged as a significant threat to human
health, veterinary health, and food safety in recent years. After the prohibition of colistin as a …

Objectives This study investigated the prevalence and characteristics of mcr-1-harbouring
Escherichia coli isolated from chickens in central China from 2014 to 2019. Methods A total …

ABSTRACT WHO considers colistin as a highest priority critically important drug for human
health, and occurrence of colistin-resistant bacteria in livestock is of health concern. The …

The emergence and global distribution of the mcr-1 gene for colistin resistance have
become a public concern because of threats to the role of colistin as the last line of defense …

Colistin is the last line of defense for the treatment of multidrug-resistant gram-negative
bacterial infections. However, colistin resistance is gradually increasing worldwide, with …