Understanding the determinants of healthy mental ageing is a priority for society today,. So
far, we know that intelligence differences show high stability from childhood to old age, and …

Pathological disturbances of mood may follow a'bipolar'course, in which normal moods
alternate with both depression and mania, or a'unipolar'course, in which only depression …

Biomarkers in psychiatry | Nature Skip to main content Thank you for visiting nature.com. You
are using a browser version with limited support for CSS. To obtain the best experience, we …

The mammalian cerebrum performs high-level sensory perception, motor control and
cognitive functions through highly specialized cortical and subcortical structures. Recent …

Viral infection during pregnancy is correlated with increased frequency of
neurodevelopmental disorders, and this is studied in mice prenatally subjected to maternal …

Genome-wide sequencing of human populations has revealed substantial variation among
genes in the intensity of purifying selection acting on damaging genetic variants. Although …

[illus. 1] The prevalence of neurodegenerative disorders is increasing, owing--in part--to
extensions in lifespan. Currently, there is no cure for any of these diseases, although not for …

Reading disability (dyslexia) is a major social, educational, and mental health problem.
Although estimates of prevalence vary, up to 10–15% of school-age children have severe …

Epigenetic modifications of DNA and histones might be crucial for understanding the
molecular basis of complex phenotypes. One reason for this is that epigenetic factors are …

Synaptic plasticity may result from changes at existing synapses or from alterations in the
number of functional synaptic connections1. In the hippocampus excitatory synaptic strength …