Antibody recognizing 4-sulfated chondroitin sulfate proteoglycans restores memory in tauopathy-induced neurodegeneration
S Yang, S Hilton, JN Alves, LM Saksida, T Bussey… - Neurobiology of …, 2017 - Elsevier
Chondroitin sulfate proteoglycans (CSPGs) are the main active component of perineuronal
nets (PNNs). Digestion of the glycosaminoglycan chains of CSPGs with chondroitinase ABC …
nets (PNNs). Digestion of the glycosaminoglycan chains of CSPGs with chondroitinase ABC …
[HTML][HTML] Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory
S Foscarin, R Raha-Chowdhury, JW Fawcett… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
Chondroitin sulfate (CS) proteoglycans in perineuronal nets (PNNs) from the central nervous
system (CNS) are involved in the control of plasticity and memory. Removing PNNs …
system (CNS) are involved in the control of plasticity and memory. Removing PNNs …
[HTML][HTML] Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology
S Yang, M Cacquevel, LM Saksida, TJ Bussey… - Experimental …, 2015 - Elsevier
Alzheimer's disease is the most prevalent tauopathy and cause of dementia. We investigate
the hypothesis that reactivation of plasticity can restore function in the presence of neuronal …
the hypothesis that reactivation of plasticity can restore function in the presence of neuronal …
Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing
S Yang, S Gigout, A Molinaro, Y Naito-Matsui… - Molecular …, 2021 - nature.com
Perineuronal nets (PNNs) are chondroitin sulphate proteoglycan-containing structures on
the neuronal surface that have been implicated in the control of neuroplasticity and memory …
the neuronal surface that have been implicated in the control of neuroplasticity and memory …
Chondroitin sulfate proteoglycans: key modulators of neuronal plasticity, long-term memory, neurodegenerative, and psychiatric disorders
X Yang - Reviews in the Neurosciences, 2020 - degruyter.com
The chondroitin sulfate proteoglycans (CSPGs) are large groups of heterogenous
proteoglycans that are mainly expressed by reactive astrocytes in the central nervous …
proteoglycans that are mainly expressed by reactive astrocytes in the central nervous …
Chondroitin 6‐sulfation regulates perineuronal net formation by controlling the stability of aggrecan
S Miyata, H Kitagawa - Neural plasticity, 2016 - Wiley Online Library
Perineuronal nets (PNNs) are lattice‐like extracellular matrix structures composed of
chondroitin sulfate proteoglycans (CSPGs). The appearance of PNNs parallels the decline …
chondroitin sulfate proteoglycans (CSPGs). The appearance of PNNs parallels the decline …
Perineuronal nets protect against amyloid β-protein neurotoxicity in cultured cortical neurons
S Miyata, Y Nishimura, T Nakashima - Brain research, 2007 - Elsevier
Perineuronal nets (PNs) consisting of chondroitin sulfate proteoglycans (CSPGs) and
hyaluronic acid are associated with distinct neuronal populations in mammalian brain …
hyaluronic acid are associated with distinct neuronal populations in mammalian brain …
The extracellular matrix in plasticity and regeneration after CNS injury and neurodegenerative disease
JW Fawcett - Progress in brain research, 2015 - Elsevier
Chondroitin sulfate proteoglycans (CSPGs) are involved in several processes relevant to
recovery of function after CNS damage. They restrict axon regeneration through their …
recovery of function after CNS damage. They restrict axon regeneration through their …
Mechanisms for modulation of neural plasticity and axon regeneration by chondroitin sulphate
S Miyata, H Kitagawa - The journal of biochemistry, 2015 - academic.oup.com
Chondroitin sulphate proteoglycans (CSPGs), consisting of core proteins linked to one or
more chondroitin sulphate (CS) chains, are major extracellular matrix (ECM) components of …
more chondroitin sulphate (CS) chains, are major extracellular matrix (ECM) components of …
[PDF][PDF] Chondroitin sulfate and neuronal disorders
S Miyata, H Kitagawa - Front Biosci (Landmark Ed), 2016 - article.imrpress.com
The brain extracellular matrix (ECM) is involved in several aspects of neuronal development,
plasticity, and pathophysiology. Chondroitin sulfate proteoglycans (CSPGs), consisting of …
plasticity, and pathophysiology. Chondroitin sulfate proteoglycans (CSPGs), consisting of …