After an infection, T cells that carry the CD8 marker are activated and undergo a
characteristic kinetic sequence of rapid expansion, subsequent contraction and formation of …

An understanding of how T cell memory is maintained is crucial for the rational design of
vaccines. Memory T cells were shown to persist indefinitely in major histocompatibility …

CCR7 is only half the story, because cells first adhere to the walls of the lymph-node vessels
using a molecule called L-selectin. So, the 'combination code'for entry of T cells to normal …

Immunological memory is one of the features that define the adaptive immune response: by
generating specific memory cells after infection or vaccination, the host provides itself with a …

Infection elicits CD4+ memory T lymphocytes that participate in protective immunity.
Although memory cells are the progeny of naïve T cells, it is unclear that all naïve cells from …

Immunological memory provides the basis for successful vaccines. It is important to
understand the properties of memory cells. There is much known about the phenotype and …

CLONAL deletion or clonal anergy establish tolerance in T cells that bear potentially
autoreactive antigen receptors1–15. Here we report that concomitant infection with the …

MEMORY is a fundamental characteristic of immunological phenomena; it is manifested by
enhanced responsiveness upon re-exposure to antigen, and its specificity forms the basis of …

Protective T-cell memory has long been thought to reside in blood and lymph nodes, but
recently the concept of immune memory in peripheral tissues mediated by resident memory …

Memory T cells maintain their numbers for long periods after antigen exposure. Here we
show that CD8+ T cells of memory phenotype divide slowly in animals. This division requires …