Effects of doxorubicin and/or cilostazol on cancer cells during liver regeneration after two-thirds hepatectomy in rats

Y Ikeda, T Matsumata, K Takenaka, M Yamagata… - Oncology, 1998 - karger.com
A rat model of liver metastases generated by intraportal injection of syngeneic tumor cells
after two-thirds hepatectomy to determine the optimal benefit of doxorubicin and/or cilostazol …

Effects of doxorubicin on cancer cells after two‐thirds hepatectomy in rats

Y Ikeda, T Matsumata, T Utsunomiya… - Journal of surgical …, 1995 - Wiley Online Library
A rat model of liver metastases generated by intraportal injection of syngeneic tumor cells
after two‐thirds hepatectomy was used to determine the optimal regional chemotherapeutic …

Liver regeneration stimulates tumor metastases

N Harun, M Nikfarjam, V Muralidharan… - Journal of Surgical …, 2007 - Elsevier
BACKGROUND: Partial hepatectomy for patients with colorectal liver metastases is
associated with a tumor recurrence rate approaching 80% post-resection. Different factors …

Tumor recurrence after partial hepatectomy for liver metastases in rats: prevention by in vivo injection of irradiated cancer cells expressing GMCSF and IL-12

B Aussilhou, Y Panis, A Alves, C Nicco… - Journal of Surgical …, 2008 - Elsevier
BACKGROUND: Adjuvant treatment could be helpful in prevent recurrence after partial
hepatectomy for liver metastases. The purpose of this study was to assess the benefit of in …

Promotion of hepatic metastases by liver resection in the rat

J Mizutani, T Hiraoka, R Yamashita… - British journal of cancer, 1992 - nature.com
In the early period following radical hepatectomy for hepatoma, recurrences in the remaining
liver are frequently found. In regenerating liver, implantation and growth of tumour cells …

A comparative study on effects of doxorubicin alone or mixed with lipiodol given through the hepatic artery or portal vein for liver tumors in rats

T Utsunomiya, T Kanematsu, T Matsumata, K Shirabe… - Oncology, 1994 - karger.com
Vascular feeding of metastatic liver tumors at early stage is uncertain. It is controversial
whether anticancer agents should be given through the hepatic artery or portal vein. In order …

[HTML][HTML] Oxaliplatin but not irinotecan impairs posthepatectomy liver regeneration in a murine model

PA Soriano, N Liu, E Castillo, B Foster… - International Journal of …, 2011 - hindawi.com
Introduction. We examined the murine hepatectomy model of liver regeneration (LR) in the
setting of neoadjuvant chemotherapy. Methods. C57BL/6 mice were randomized to receive …

Arguments against toxic effects of chemotherapy on liver injury and regeneration in an experimental model of partial hepatectomy

A Rickenbacher, ML DeOliveira, Y Tian… - Liver …, 2011 - Wiley Online Library
Background: New chemotherapy regimens are increasingly used in metastatic colorectal
cancer to the liver before surgery. Some clinical observations have suggested that …

Experimental colorectal liver metastases: influence of sex, immunological status and liver regeneration

Y Panis, B Nordlinger, R Delelo, JP Herve, J Infante… - Journal of …, 1990 - Elsevier
The liver is the most frequent site of metastases from colon cancer. To improve our
knowledge of liver metastases and to develop new adjuvant therapies, a good animal model …

Preliminary report of tumor metastasis during liver regeneration after hepatic resection in rats

Y Ikeda, T Matsumata, K Takenaka, O Sasaki… - European journal of …, 1995 - ejso.com
In an attempt to ascertain possible facilitation of tumor metastasis during liver regeneration
after hepatectomy, a series of experiments in rats was carried out using the RBT-1 …