Acute hepatic response to aflatoxin B1 in rats fed a methyl-deficient, amino acid-defined diet

R Mehta, JS Campbell, GW Laver, R Stapley, R Mueller - Cancer letters, 1993 - Elsevier
In order to evaluate the relative contribution of aflatoxin B 1 (AFB 1)-induced toxicity towards
a methyl-deficient diet influenced AFB 1 arcinogenesis, a no-observed-effect-level (NOEL) …

Effect of Lifetime Exposure to Aflatoxin B1 in Rats

JM Ward, JM Sontag, EK Weisburger… - Journal of the National …, 1975 - academic.oup.com
Aflatoxin B1 was feci at 2 ppm in the diet to a group of pregnant F344 rats from the time of
conception; it was then fed to their offspring until death. This diet was also given to another …

Dietary protein and experimental carcinogenesis

WJ Visek - Essential Nutrients in Carcinogenesis, 1986 - Springer
This review summarizes selected information about the influence of proteins, protein-fat
interactions, and calorie intake on carcinogenesis. Most of the definitive studies concerning …

Mechanisms of Dietary Modification of Aflatoxin B1 Carcinogenesis

G Bailey, M Taylor, D Selivonchick, T Eisele… - Genetic toxicology: an …, 1982 - Springer
Trout were fed a range of dietary components which altered their carcinogenic response to
aflatoxin B 1 (AFB 1). Dietary protein at levels substantially exceeding nutritional …

Modification by beet and cabbage diets of aflatoxin B1-induced rat plasma α-foetoprotein elevation, hepatic tumorigenesis, and mutagenicity of urine

JN Boyd, JG Babish, GS Stoewsand - Food and Chemical Toxicology, 1982 - Elsevier
Weanling male Fischer rats were fed a purified diet or diets containing 25%(w/w) freeze-
dried ground beets or cabbage with or without 1 ppm aflatoxin B 1 (AFB 1) for 26 wk. In 3–7 …

Influence of different levels of dietary casein on initiation of male rat liver carcinogenesis with a single dose of aflatoxin B1

A Blanck, B Lindhe, IP Hällström, P Lindeskog… - …, 1992 - academic.oup.com
To analyze the influence of different levels of dietary casein on the initiation process, male
Wistar rats, pair-fed on isocaloric diets containing 5, 15 or 40% casein were initiated with a …

The effects of dietary restriction and aging on in vivo and in vitro binding of aflatoxin B1 to cellular DNA.

MW Chou, RA Pegram, P Gao, SR Hansard… - Biomedical and …, 1991 - europepmc.org
Laboratory animals maintained on a reduced calorie but nutritionally adequate diet have
extended life spans and lowered incidences of spontaneous and chemically induced …

Nutritional modulation of the carcinogenesis process: targets and examples

SD Hursting - Cancer and Nutrition, 2000 - karger.com
The ultimate goal of carcinogenesis research is to achieve an understanding of the
processes involved in the induction of human cancer to an extent that will allow intervention …

α-fetoprotein and γ-glutamyl transpeptidase response in rats fed aflatoxin B1

JN Boyd, N Misslbeck, GS Stoewsand - Toxicology and Applied …, 1982 - Elsevier
Weanling, male, Fischer rats were fed a semipurified diet containing 0, 0.1, 0.5, 1.0, or 2.0
ppm aflatoxin B1 (AB1). Plasma α-fetoprotein (AFP) concentrations were determined weekly …

The Generation of Cancer: Initiation, promotion, progression and the multiple influences of the environment

RW Stoddart - Nutrition and Health, 1983 - journals.sagepub.com
Carcinogenesis is a multi-stage process, conventionally divided into initiation, promotion
and progression. Most carcinogens are initiators, but promoters may be equally important …