The expression, localization, and function of connexins, the protein subunits that comprise
gap junctions, are often altered in cancer. In addition to cell–cell coupling through gap …

Connexin-and pannexin (Panx)-formed hemichannels (HCs) and gap junctions (GJs)
operate an interaction with the extracellular matrix and GJ intercellular communication …

Malignant cells usually show altered gap junctional intercellular communication and are
often associated with aberrant expression or localization of connexins. Transfection of …

Prompted by the notion that the membrane channels in gap junctions conduct growth-
regulating signals from cell to cell, we transferred the α1 gene for the channel protein …

Connexins constitute a large family of trans-membrane proteins that allow intercellular
communication and the transfer of ions and small signaling molecules between cells …

Additive effects against tumor cells might be achieved by combining anti‐neoplastic agents
directed against one or more altered mechanisms in cancer. We investigated the …

The inhibition of gap‐junctional intercellular communication (GJIC) between initiated and
surrounding normal cells by tumor promoters is believed to be important in the promotion …

Animal tumor models have demonstrated a close correlation between gap junctional,
intercellular communication (GJIC) and tumor metastasis. To examine GJIC levels in human …

Cellular communication mediated by gap junction channels and hemichannels, both
composed of connexin proteins, constitutes two acknowledged regulatory platforms in the …

Gap junctional intercellular communication (GJIC) is recognized as playing an important role
in normal cell proliferation and development. Chemically induced alteration of GJIC has …