Potent apoptosis-inducing activity of erypoegin K, an isoflavone isolated from Erythrina poeppigiana, against human leukemia HL-60 cells

K Hikita, N Hattori, A Takeda, Y Yamakage… - Journal of natural …, 2018 - Springer
Erypoegin K is an isoflavone isolated from the stem bark of Erythrina poeppigiana. It
contains a furan group at the A-ring of the core isoflavone structure and can inhibit the …

[HTML][HTML] Induction of enantio-selective apoptosis in human leukemia HL-60 cells by (S)-erypoegin K, an isoflavone isolated from Erythrina poeppigiana

K Hikita, S Saigusa, Y Takeuchi, H Matsuyama… - Bioorganic & Medicinal …, 2020 - Elsevier
Erypoegin K, an isoflavone isolated from the stem bark of Erythrina poeppigiana, has potent
apoptosis-inducing effect on human leukemia HL-60 cells. Erypoegin K has a chiral carbon …

Inhibitory Effect of Isoflavones from Erythrina poeppigiana on the Growth of HL-60 Human Leukemia Cells through Inhibition of Glyoxalase I

K Hikita, S Yamada, R Shibata… - Natural product …, 2015 - journals.sagepub.com
It has been reported that many malignant human tissues, including breast, colon, and lung
cancers, may show an elevated expression of glyoxalase I (GLO I). GLO I catalyzes the …

Induction of Apoptosis in Human Promyelocytic Leukemia HL60 Cells by an Extract From Erythrina suberosa Stem Bark

SK Agrawal, M Agrawal, PR Sharma, BD Gupta… - Nutrition and …, 2011 - Taylor & Francis
In this study, the apoptosis-inducing effect of an alcoholic extract from Erythrina suberosa
stem bark (ESB) was investigated using human promyelocytic leukemia HL60 cells. Cell …

[HTML][HTML] Eupalinolide O, a novel sesquiterpene lactone from Eupatorium lindleyanum DC., induces cell cycle arrest and apoptosis in human MDA-MB-468 breast …

B Yang, Y Zhao, C Lou, H Zhao - Oncology Reports, 2016 - spandidos-publications.com
Sesquiterpene lactones have been confirmed to have potential antitumor activity. Here, we
demonstrated that Eupalinolide O (EO), a novel sesquiterpene lactone isolated from …

The anticancer potential of flavonoids isolated from the stem bark of Erythrina suberosa through induction of apoptosis and inhibition of STAT signaling pathway in …

S Kumar, AS Pathania, AK Saxena… - Chemico-biological …, 2013 - Elsevier
Erythrina suberosa is an ornamental tall tree found in India, Pakistan, Nepal, Bhutan, Burma,
Thailand and Vietnam. We have isolated four known distinct metabolites designated as α …

Eudesmols induce apoptosis through release of cytochrome c in HL-60 cells

DM Hoang, TN Trung, L He, DT Ha, MS Lee… - Natural Product …, 2010 - koreascience.kr
We verified that the apoptosis activities were examined by DNA fragmentation, flow
cytometric analysis with annexin V staining, activation of caspase-3, and cytochrome c …

Cassaine Diterpenoid Amide from Stem Bark of Erythrophleum fordii Suppresses Cytotoxic and Induces Apoptosis of Human Leukemia Cells

TTT Nguyen, DC To, PHT Vo, TH Tran, PH Nguyen… - Molecules, 2020 - mdpi.com
Cassaine diterpenoids amides from the stem bark of Vietnamese Erythrophleum fordii Oliver
were screened for their cytotoxic activity against human cancer cells. The cell proliferation …

Effects of Euphorbiae lathyridis Semen on cell apoptosis in HT-29 human colon cancer cells

JH Lee, SJ Jung, YK Park - The Korea Journal of Herbology, 2007 - koreascience.kr
Objectives: In this study, we investigate that Euphorbiae lathyridis Semen extract contributes
to growth inhibitory effect and anti-cancer activity on the HT-29 human colon cancer cells …

β‐Eudesmol induces JNK‐dependent apoptosis through the mitochondrial pathway in HL60 cells

Y Li, T Li, C Miao, J Li, W Xiao, E Ma - Phytotherapy Research, 2013 - Wiley Online Library
β‐eudesmol, a natural sesquiterpenol present in a variety of Chinese herbs, is known to
inhibit the proliferation of human tumor cells. However, the molecular mechanisms of the …