[HTML][HTML] The modulation of oxygen radical production by nitric oxide in mitochondria
TM Sarkela, J Berthiaume, S Elfering, AA Gybina… - Journal of Biological …, 2001 - ASBMB
Biological systems that produce or are exposed to nitric oxide (NO⋅) exhibit changes in the
rate of oxygen free radical production. Considering that mitochondria are the main …
rate of oxygen free radical production. Considering that mitochondria are the main …
Nitric oxide produced in rat liver mitochondria causes oxidative stress and impairment of respiration after transient hypoxia
L Schild, T Reinheckel, M Reiser, TFW Horn… - The FASEB …, 2003 - Wiley Online Library
Nitric oxide (NO) is produced in mam‐mals by different isoforms of NO synthase (NOS), in‐
cluding the constitutive mitochondrial enzyme (mtNOS). Here we demonstrate that the …
cluding the constitutive mitochondrial enzyme (mtNOS). Here we demonstrate that the …
Oxygen-dependent regulation of mitochondrial energy metabolism by nitric oxide
Y Takehara, T Kanno, T Yoshioka, M Inoue… - Archives of Biochemistry …, 1995 - Elsevier
To elucidate the role of nitric oxide (NO) in the regulation of mitochondrial function, the effect
of NO on energy transfer reactions was examined under different oxygen tensions …
of NO on energy transfer reactions was examined under different oxygen tensions …
[HTML][HTML] Production of nitric oxide by mitochondria
C Giulivi, JJ Poderoso, A Boveris - Journal of Biological Chemistry, 1998 - ASBMB
The production of NO⋅ by mitochondria was investigated by electron paramagnetic
resonance using the spin-trapping technique, and by the oxidation of oxymyoglobin. Percoll …
resonance using the spin-trapping technique, and by the oxidation of oxymyoglobin. Percoll …
Do mitochondria make nitric oxide? no?
YMS Tay, KS Lim, FS Sheu, A Jenner… - Free radical …, 2004 - Taylor & Francis
Several papers have claimed that mitochondria contain nitric oxide synthase (NOS) and
make nitric oxide (NO•) in amounts sufficient to affect mitochondrial respiration. However, we …
make nitric oxide (NO•) in amounts sufficient to affect mitochondrial respiration. However, we …
Oxygen dependence of mitochondrial nitric oxide synthase activity
S Alvarez, LB Valdez, T Zaobornyj, A Boveris - … and biophysical research …, 2003 - Elsevier
The effect of O2 concentration on mitochondrial nitric oxide synthase (mtNOS) activity and
on O2− production was determined in rat liver, brain, and kidney submitochondrial …
on O2− production was determined in rat liver, brain, and kidney submitochondrial …
Functional implications of nitric oxide produced by mitochondria in mitochondrial metabolism
C GIULIVI - Biochemical Journal, 1998 - portlandpress.com
The effects of endogenous production of NO•, catalysed by the mitochondrial nitric oxide
synthase (NOS), on mitochondrial metabolism were studied. The respiratory rates of intact …
synthase (NOS), on mitochondrial metabolism were studied. The respiratory rates of intact …
Mitochondrial NO and reactive nitrogen species production: does mtNOS exist?
It is more than 10 years now that mitochondria are suspected to be sources of nitric oxide
(NO). This hypothesis is intriguing since NO has multiple targets within the organelle and it is …
(NO). This hypothesis is intriguing since NO has multiple targets within the organelle and it is …
Regulation of mitochondrial respiration by oxygen and nitric oxide
A Boveris, LE Costa, JJ Poderoso… - Annals of the New …, 2000 - Wiley Online Library
Although the regulation of mitochondrial respiration and energy production in mammalian
tissues has been exhaustively studied and extensively reviewed, a clear understanding of …
tissues has been exhaustively studied and extensively reviewed, a clear understanding of …
Neuronal nitric oxide synthase controls enzyme activity pattern of mitochondria and lipid metabolism
L Schild, I Jaroscakova, U Lendeckel, G Wolf… - The FASEB …, 2006 - Wiley Online Library
Mitochondria are affected by endogenous nitric oxide (NO). Besides effects of NO on
mitochondrial enzymes and the stimulation of mitochondrial H2O2 production, a NO …
mitochondrial enzymes and the stimulation of mitochondrial H2O2 production, a NO …