Extended storage of granulocyte concentrates mobilized by G‐CSF with/without dexamethasone and collected by bag separation method

K Mochizuki, A Kikuta, H Ohto, K Nemoto… - Transfusion …, 2007 - Wiley Online Library
summary The aim of this study was to examine the extended storage of granulocyte
concentrates mobilized by granulocyte‐colony‐stimulating factor (G‐CSF) with/without …

Storage of G–CSF‐mobilized granulocyte concentrates

T Lightfoot, SF Leitman, DF Stroncek - Transfusion, 2000 - Wiley Online Library
BACKGROUND: Current standards limit granulocyte storage to 24 hours. Since G–CSF
inhibits granulocyte apoptosis, it may be possible to store G–CSF‐mobilized granulocytes …

Functional state of steroid-versus G-CSF-mobilized granulocytes: considerations about the storage of granulocyte concentrates for neutropenic patients

A Schmitt, P Reinhardt, M Schmitt… - Transfusion Medicine …, 2002 - karger.com
Background: High yields of granulocytes mobilized with G-CSF sparked new enthusiasm for
transfusion in patients with severe neutropenia. The in vitro and in vivo function of …

Evaluation of solutions for the storage of granulocyte colony‐stimulating factor‐mobilized granulocyte concentrates

T Lightfoot, J Gallelli, K Matsuo, SW Kwon… - Vox …, 2001 - Wiley Online Library
Background High cell counts in granulocyte colony‐stimulating factor (G‐CSF)‐mobilized
granulocytes are detrimental to concentrate storage. An eightfold dilution with autologous …

Kinetics of G–CSF‐induced granulocyte mobilization in healthy subjects: effects of route of administration and addition of dexamethasone

DF Stroncek, CL Matthews, D Follmann… - Transfusion, 2002 - Wiley Online Library
BACKGROUND: Granulocyte donors are frequently given G–CSF with or without
dexamethasone approximately 18 hours before apheresis to increase cell yields. The …

Effective storage of granulocytes collected by centrifugation leukapheresis from donors stimulated with granulocyte–colony‐stimulating factor

K Hubel, E Rodger, JM Gaviria, TH Price, DC Dale… - …, 2005 - Wiley Online Library
BACKGROUND: Donor stimulation with granulocyte–colony‐stimulating factor (G‐CSF) has
increased the number of neutrophils (PMNs) that can be collected for granulocyte …

[PDF][PDF] Preparation of granulocyte concentrates by apheresis

G Leitner, S Panzer, HW Reesink, G Stiegler… - Vox …, 2010 - academia.edu
Bacterial and fungal infections still are life-threatening complications in
immunocompromised patients. Transfusion of allogeneic granulocytes, collected by donor …

Administration of G–CSF plus dexamethasone producesgreater granulocyte concentrate yields while causing nomore donor toxicity than G–CSF alone

DF Stroncek, YY Yau, J Oblitas, SF Leitman - Transfusion, 2001 - Wiley Online Library
BACKGROUND: G–CSF with or without dexamethasone is becoming the standard agent for
mobilizing granulocytes for transfusion. The purpose of this study was to determine if the …

Combined administration of G–CSF and dexamethasone for the mobilization of granulocytes in normal donors: optimization of dosing

WC Liles, E Rodger, DC Dale - Transfusion, 2000 - Wiley Online Library
BACKGROUND: The clinical utility of neutrophil (polymorphonuclear leukocyte, PMN)
transfusion therapy has been compromised, in part, by the inability to obtain sufficient …

Granulocyte colony-stimulating factor-mobilized granulocyte concentrate transfusions

TH Price - Current Opinion in Hematology, 1998 - journals.lww.com
Granulocyte transfusion therapy has been used infrequently in the last 10 to 15 years, in
large part because its efficacy in the treatment of infected neutropenic patients has not been …